2,4,6-Triaminopimelinsaeure | 48065-37-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,4,6-Triaminopimelinsaeure
• 英文别名: 2,4,6-Triaminoheptanedioic acid；2,4,6-triaminoheptanedioic acid
• CAS: 48065-37-8
• 化学式: C₇H₁₅N₃O₄
• 分子量: 205.214
• InChiKey: DYDIAQYPMYZMDR-UHFFFAOYSA-N

物化性质

• 沸点：
  519.7±50.0 °C(Predicted)
• 密度：
  1.410±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -7.1
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  153
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  diethyl 2-acetamido-2-(3-bromo-2-oxopropyl)malonate 以 N,N-二甲基甲酰胺 为溶剂， 生成 2,4,6-Triaminopimelinsaeure
  参考文献：
  名称：

  Hanus,J. et al., Collection of Czechoslovak Chemical Communications, 1973, vol. 38, p. 1212 - 1220

  摘要：

  DOI：

文献信息

• PROCESS FOR THE PRODUCTION OF L-LYSINE USING CORYNEFORM BACTERIA
  申请人：Degussa AG

  公开号：EP1525321A1

  公开（公告）日：2005-04-27
• Process for the production of L-lysine using coryneform bacteria
  申请人：Degussa AG

  公开号：US20040067561A1

  公开（公告）日：2004-04-08

  A process for the production of L-lysine, comprising: a) fermentation of the L-lysine producing coryneform bacteria that are at least sensitive to diaminopimelic acid analogues, in particular 4-hydroxydiaminopimelic acid; b) enrichment of the L-lysine in the medium or in the bacterial cells; and optionally c) isolation of the L-lysine or L-lysine-containing feedstuffs additive from the fermentation broth, so that ≧0 to 100% of the constituents from the fermentation broth and/or from the biomass are present, and optionally bacteria are used in which in addition further genes of the biosynthesis pathway of L-lysine are enhanced, or bacteria are used in which the metabolic pathways that reduce the formation of L-lysine are at least partially switched off.
• [EN] PROCESS FOR THE PRODUCTION OF L-LYSINE USING CORYNEFORM BACTERIA<br/>[FR] PROCEDE DE PRODUCTION DE L-LYSINE AU MOYEN DE BACTERIES CORYNEFORMES
  申请人：DEGUSSA

  公开号：WO2004013340A2

  公开（公告）日：2004-02-12

  The invention relates to a process for the production of L-lysine, in which the following steps are carried out a) fermentation of the L-lysine producing coryneform bacteria that are at least sensitive to diaminopimelic acid analogues, in particular 4-hydroxydiaminopimelic acid; b) enrichment of the L-lysine in the medium or in the bacterial cells; and optionally c) isolation of the L-lysine or L-lysine-containing feedstuffs additive from the fermentation broth, so that ≥ 0 to 100% of the constituents from the fermentation broth and/or from the biomass are present, and optionally bacteria are used in which in addition further genes of the biosynthesis pathway of L-lysine are enhanced, or bacteria are used in which the metabolic pathways that reduce the formation of L-lysine are at least partially switched off.
• [EN] PROCESS FOR THE PRODUCTION OF L-LYSINE USING CORYNEFORM BACTERIA<br/>[FR] PROCEDE DE PRODUCTION DE L-LYSINE FAISANT APPEL AUX BACTERIES CORYNEFORMES
  申请人：DEGUSSA

  公开号：WO2004013341A1

  公开（公告）日：2004-02-12

  The invention relates to a process for the production of L-lysine, in which the following steps are carried out: a) fermentation of the L-lysine producing coryneform bacteria that are at least resistant to diaminopimelic acid analogues, in particular 4-hydroxydiaminopimelic acid; b) enrichment of the L-lysine in the medium or in the bacterial cells; and optionally c) isolation of the L-lysine or L-lysine-containing feedstuffs additive from the fermentation broth, so that ≥ 0 to 100% of the constituents from the fermentation broth and/or from the biomass are present, and optionally bacteria are used in which in addition further genes of the biosynthesis pathway of L-lysine are enhanced, or bacteria are used in which the metabolic pathways that reduce the formation of L-lysine are at least partially switched off.
• [EN] PROCESS FOR THE PRODUCTION OF L-LYSINE<br/>[FR] PROCEDE DE PRODUCTION DE L-LYSINE
  申请人：DEGUSSA

  公开号：WO2005021771A2

  公开（公告）日：2005-03-10

  The invention relates to an improved process for the production of L-lysine by fermentation using L-lysine-producing coryneform bacteria.