acetic acid-(3,4-dimethyl-benzyl ester) | 13651-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: acetic acid-(3,4-dimethyl-benzyl ester)
• 英文别名: 4¹-Acetoxy-1.2.4-trimethyl-benzol；Essigsaeure-(3,4-dimethyl-benzylester)；(3.4-Dimethyl-benzyl)-acetat；3,4-Dimethylbenzylacetat；3.4-Dimethylbenzylacetat；3,4-Dimethylbenzyl acetate；(3,4-dimethylphenyl)methyl acetate
• CAS: 13651-58-6
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: ZEINVEXGTNYWJK-UHFFFAOYSA-N

物化性质

• 沸点：
  249.1±9.0 °C(Predicted)
• 密度：
  1.019±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  邻二甲苯 在 二硫化碳 、 四氯化锡 、 溶剂黄146 作用下， 生成 acetic acid-(3,4-dimethyl-benzyl ester)
  参考文献：
  名称：

  Sommelet, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1913, vol. 157, p. 1445

  摘要：

  DOI：

文献信息

• SUBSTITUTED IMIDAZOLES
  申请人：CHUBB NATHAN ANTHONY LOGAN

  公开号：US20070167506A1

  公开（公告）日：2007-07-19

  This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.

  本发明涉及一系列α取代的2-苄基取代咪唑化合物及其药用可接受盐和溶剂化合物，包括这些化合物的组合物、合成过程以及它们作为驱虫剂的用途。
• ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES
  申请人：Marfat Anthony

  公开号：US20070161681A1

  公开（公告）日：2007-07-12

  Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of the formula: wherein the substituents are as defined in the specification.

  以下化合物可用作PDE4的抑制剂，用于治疗由嗜酸性粒细胞的活化和脱颗粒调控的疾病，特别是哮喘、慢性支气管炎和慢性阻塞性肺疾病，其化学式如下：其中取代基如规范中所定义。
• BERGMAN J.; ENGMAN L., TETRAHEDRON LETT., 1978, NO 35, 3279-3282
  作者：BERGMAN J.、 ENGMAN L.

  DOI：——

  日期：——
• Process for synthesizing heliotropine and its derivatives
  申请人：Borzatta Valerio

  公开号：US20070100167A1

  公开（公告）日：2007-05-03

  A new high-yield, easily industrialized process for synthesizing compounds of formula (IV), in which X 1 and X 2 , the same or different, are linear or branched C1-C8 alkyls, n and m are 0, 1 or 2, with the proviso that n and m are not simultaneously 0; or (OX 1 )n and (OX 2 )m taken together form an O-T-O group where T is chosen from —CH 2 —, —CH 2 CH 2 , —CH 2 CH 2 CH 2 —, —C(CH 3 ) 2 —. The process comprises treating a chloromethyl derivative (I) with an alkaline acetate to form the intermediate acetylderivative (II); the intermediate (II) is to hydrolysed to form the alcohol (III); the alcohol (III) is then oxidised in the presence of air and catalysts to obtain the desired derivative (IV). The process runs its course within a short period of time, with high yields and high selectivity; in addition, the process does not require purification and separation of the intermediates and can therefore be favourably conducted in a single batch.
• US7183293B2
  申请人：——

  公开号：US7183293B2

  公开（公告）日：2007-02-27