2-甲基-6-甲氧基-5-异丙基吡嗪 | 56343-37-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 2-甲基-6-甲氧基-5-异丙基吡嗪
• 英文名称: 2-methoxy-3-isopropyl-6-methylpyrazine
• 英文别名: Pyrazine, 3-methoxy-5-methyl-2-(1-methylethyl)-；3-methoxy-5-methyl-2-propan-2-ylpyrazine
• CAS: 56343-37-4
• 化学式: C₉H₁₄N₂O
• 分子量: 166.223
• InChiKey: VALFOZLZVWSAPI-UHFFFAOYSA-N

物化性质

• 保留指数：
  1440

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-甲基-6-甲氧基-5-异丙基吡嗪 在 potassium diisopropylamide 、 对甲苯磺酸 、 三苯基膦 、 肼 、 偶氮二甲酸二乙酯 作用下， 生成 6-(3-nitroguanidinopropyl)-3-isopropyl-2-methoxypyrazine
  参考文献：
  名称：

  Synthesis of Argvalin and Its Related Compound

  摘要：

  DOI：

  10.3987/com-87-4389
• 作为产物：
  描述：

  sodium methylate 、 3-氯-2-异丙基-5-甲基吡嗪 以83%的产率得到2-甲基-6-甲氧基-5-异丙基吡嗪
  参考文献：
  名称：

  Synthesis of Argvalin and Its Related Compound

  摘要：

  DOI：

  10.3987/com-87-4389

文献信息

• GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
  申请人：Huang Xianhai

  公开号：US20110027264A1

  公开（公告）日：2011-02-03

  This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula: Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).

  本发明提供了一种新型化合物，其为γ-分泌酶调节剂。该化合物的化学式为：同时还揭示了使用式(I)的化合物调节γ-分泌酶活性和治疗阿尔茨海默病的方法。
• PROCEDE DE FABRICATION DE PROTEINES VEGETALES SOLUBLES ET FONCTIONNELLES, PRODUITS OBTENUS ET UTILISATIONS
  申请人：ROQUETTE FRERES

  公开号：EP2555634A1

  公开（公告）日：2013-02-13
• GAMMA SECRETASE MODULATORS
  申请人：Zhu Zhaoning

  公开号：US20120129846A1

  公开（公告）日：2012-05-24

  In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
• Process for Manufacturing Soluble and Functional Plant Proteins, Products Obtained and Uses
  申请人：Dhalleine Claire

  公开号：US20130017310A1

  公开（公告）日：2013-01-17

  The invention relates to a process for manufacturing soluble and functional plant proteins, characterized in that it comprises at least one functionalizing step that consists of a treatment of 0.01 s to 1 s constituted of a step of heating plant proteins at a temperature of 100° C. to 160° C. and a step of cooling the heated plant proteins. The invention also relates to a process for converting non-functional plant proteins to functional proteins. Another subject of the invention is a plant protein, characterized in that it has a solubility in water of greater than 50% (with the exception of a potato protein for which the solubility in water is 25%), an emulsifying capacity between 700,000 mPa·s and 1,200,000 mPa·s for a sample directly placed at 4° C. for 24 h (with the exception of a potato protein for which the emulsifying capacity for a sample directly placed at 4° C. for 24 h is between 400,000 mPa·s and 600,000 mPa·s) and between 500,000 mPa·s and 1,100,000 mPa·s for a sample treated at 75° C. then placed at 4° C. for 24 h and an emulsifying capacity between 70% and 95%. A further subject of the invention is the use of said plant protein in the manufacture of food.
• US9573936B2
  申请人：——

  公开号：US9573936B2

  公开（公告）日：2017-02-21