Tetrakis(2-carbethoxyethyl)methane | 10428-70-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Tetrakis(2-carbethoxyethyl)methane
• 英文别名: 4,4-bis-(2-ethoxycarbonyl-ethyl)-heptanedioic acid diethyl ester；Tetrakis-(β-carboaethoxyaethyl)-methan；methanetetrapropionic acid tetraethyl ester；Diethyl 4,4-bis(3-ethoxy-3-oxopropyl)heptanedioate
• CAS: 10428-70-3
• 化学式: C₂₁H₃₆O₈
• 分子量: 416.512
• InChiKey: ZMSNGFGNJPSDBA-UHFFFAOYSA-N

物化性质

• 沸点：
  453.5±45.0 °C(Predicted)
• 密度：
  1.070±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  29
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  Tetrakis(2-carbethoxyethyl)methane 在 lithium aluminium tetrahydride 、 硫酸 、 氢溴酸 作用下， 以 乙醚 、 水 、 乙腈 为溶剂， 生成 Tetrakis-(3-cyanopropyl)-methan
  参考文献：
  名称：

  新化合物：对称取代的四烷基甲烷。

  摘要：

  DOI：

  10.1002/jps.2600601148
• 作为产物：
  描述：

  四(2-氰基乙基)甲烷 在 硫酸 盐酸 作用下， 反应 30.0h， 生成 Tetrakis(2-carbethoxyethyl)methane
  参考文献：
  名称：

  Micelles series. 31. Building blocks for cascade polymers. 11. Synthesis of functionalized cascade cores: tetrakis(.omega.-bromoalkyl)methanes

  摘要：

  A series of tetrakis(bromoalkyl)methanes was synthesized and characterized. The tetrakis(3-bromopropyl)methane was chosen as ideal core to cascade polymers, since it undergoes facile substitution with bulky nucleophiles, denoting the need for at least three carbon atoms between the quaternary center and the leaving group to circumvent major steric problems caused by the core carbon. The readily available 4-nitro-4-(3-hydroxypropyl)-1,7-heptanediol was used to afford a novel entry to tetrakis(3-bromopropyl)methane as well as other building blocks to cascade polymers.

  DOI：

  10.1021/jo00056a023

文献信息

• A pneumatic tire having a rubber component containing a dendrimer
  申请人：THE GOODYEAR TIRE & RUBBER COMPANY

  公开号：EP1177919A2

  公开（公告）日：2002-02-06

  There is disclosed a pneumatic tire having a rubberized component comprising: (a) 100 parts by weight of at least one rubber containing olefinic unsaturation; and (b) 1 to 50 phr of a dendrimer.

  本发明公开了一种充气轮胎，其橡胶部件包括 (a) 至少一种含有烯烃不饱和度的橡胶，按重量计为 100 份；以及 (b) 1 至 50 phr 的树枝状聚合物。
• Pneumatic tire having a rubber component containing a dendrimer
  申请人：——

  公开号：US20020068796A1

  公开（公告）日：2002-06-06

  There is disclosed a pneumatic tire having a rubberized component comprising: (a) 100 parts by weight of at least one rubber containing olefinic unsaturation; and (b) 1 to 50 phr of a dendrimer.

  本发明公开了一种充气轮胎，其橡胶成分包括 (a) 至少一种含有烯烃不饱和度的橡胶，按重量计为 100 份；以及 (b) 1 至 50 phr 的树枝状聚合物。
• Spirans. XIII. 3,9-Disubstituted Spiro[5.5]undecane Compounds
  作者：Leonard Rice、Kenneth Scott

  DOI：10.1021/jo01281a602

  日期：1967.6
• US6889735B2
  申请人：——

  公开号：US6889735B2

  公开（公告）日：2005-05-10
• Micelles series. 31. Building blocks for cascade polymers. 11. Synthesis of functionalized cascade cores: tetrakis(.omega.-bromoalkyl)methanes
  作者：George R. Newkome、Sadao Arai、Frank R. Fronczek、Charles N. Moorefield、Xiaofeng Lin、Claus D. Weis

  DOI：10.1021/jo00056a023

  日期：1993.2

  A series of tetrakis(bromoalkyl)methanes was synthesized and characterized. The tetrakis(3-bromopropyl)methane was chosen as ideal core to cascade polymers, since it undergoes facile substitution with bulky nucleophiles, denoting the need for at least three carbon atoms between the quaternary center and the leaving group to circumvent major steric problems caused by the core carbon. The readily available 4-nitro-4-(3-hydroxypropyl)-1,7-heptanediol was used to afford a novel entry to tetrakis(3-bromopropyl)methane as well as other building blocks to cascade polymers.