(Z)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-1-phenylbutane-1,3-dione | 1084801-29-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-1-phenylbutane-1,3-dione
• 英文别名: (2Z)-2-(2-oxo-1H-indol-3-ylidene)-1-phenylbutane-1,3-dione
• CAS: 1084801-29-5
• 化学式: C₁₈H₁₃NO₃
• 分子量: 291.306
• InChiKey: CKDYPUFWHHRMFV-NXVVXOECSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  63.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-苯基-1,3-丁二酮 、 2-硝基-1H-吲哚 在 Mn(OAc)3*2H₂₀ 作用下， 以 溶剂黄146 为溶剂， 反应 0.25h， 以27%的产率得到(E)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-1-phenylbutane-1,3-dione
  参考文献：
  名称：

  Mn(III)-based radical addition reactions of 2-nitroindole with activated CH compounds

  摘要：

  2-Nitroindole undergoes addition reactions with the radicals generated from active CH compounds upon treatment with Mn(OAc)(3)center dot 2H(2)O to afford the corresponding 3-substituted-2-nitroindoles in 27-66% yields. Products of the methylene addition reactions undergo a subsequent in situ Nef reaction to afford 2-oxoindolin-3-ylidenes. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.09.020

文献信息

• Mn(III)-based radical addition reactions of 2-nitroindole with activated CH compounds
  作者：Dmitry A. Androsov、Tara L.S. Kishbaugh、Gordon W. Gribble

  DOI：10.1016/j.tetlet.2008.09.020

  日期：2008.11

  2-Nitroindole undergoes addition reactions with the radicals generated from active CH compounds upon treatment with Mn(OAc)(3)center dot 2H(2)O to afford the corresponding 3-substituted-2-nitroindoles in 27-66% yields. Products of the methylene addition reactions undergo a subsequent in situ Nef reaction to afford 2-oxoindolin-3-ylidenes. (C) 2008 Elsevier Ltd. All rights reserved.