indol-3-yl-methanesulfonic acid | 25177-75-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: indol-3-yl-methanesulfonic acid
• 英文别名: Indol-3-yl-methansulfonsaeure；(β-Indolyl)-methan-sulfonsaeure；1H-Indole-3-methanesulfonic acid；1H-indol-3-ylmethanesulfonic acid
• CAS: 25177-75-7
• 化学式: C₉H₉NO₃S
• 分子量: 211.241
• InChiKey: KGGXFLJSRHWJTP-UHFFFAOYSA-N

物化性质

• 密度：
  1.545±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  78.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  芦竹碱 在 甲醇 、 sodium hydrogensulfite 作用下， 生成 indol-3-yl-methanesulfonic acid
  参考文献：
  名称：

  Wieland et al., Justus Liebigs Annalen der Chemie, 1949, vol. 561, p. 47,51

  摘要：

  DOI：

文献信息

• Erdtman; Pettersson, Acta Chemica Scandinavica (1947), 1949, vol. 3, p. 904
  作者：Erdtman、Pettersson

  DOI：——

  日期：——
• USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES
  申请人：Veijlen N.V.

  公开号：EP1670444A2

  公开（公告）日：2006-06-21
• [EN] USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS<br/>[FR] UTILISATION DE COMPOSES POUVANT ACCROITRE LE NIVEAU SERIQUE D'IGF-1 POUR PREPARATION D'UNE COMPOSITION THERAPEUTIQUE DESTINEE AU TRAITEMENT DE DIVERS ETATS PATHOLOGIQUES ASSOCIES A UN NIVEAU SERIQUE D'IGF-1 REDUIT CHEZ LES HUMAINS ET LES ANIMAUX
  申请人：VEIJLEN N V

  公开号：WO2005039546A2

  公开（公告）日：2005-05-06

  The present invention relates to the use of one or more compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition, in particular in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome. The same composition can also be used by patients suffering from depression, Alzheimer disease, irritated bowel syndrome, osteoporosis, type 2 diabetes, or for anti-aging, immune therapy and recovery after exercise. The composition also has a use in veterinary applications for increasing the growth and immunity in animals.
• Wieland et al., Justus Liebigs Annalen der Chemie, 1949, vol. 561, p. 47,51
  作者：Wieland et al.

  DOI：——

  日期：——