2-羟基-4-氧代-16-十七碳炔-1-基乙酸酯 | 24607-10-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-羟基-4-氧代-16-十七碳炔-1-基乙酸酯
• 英文名称: 1-Acetoxy-2-hydroxy-16-heptadecyn-4-one
• 英文别名: (2-hydroxy-4-oxoheptadec-16-ynyl) acetate
• CAS: 24607-10-1
• 化学式: C₁₉H₃₂O₄
• 分子量: 324.5
• InChiKey: HZHSVQVECJXVRP-UHFFFAOYSA-N

物化性质

• 熔点：
  47-49 °C
• 沸点：
  453.9±30.0 °C(Predicted)
• 密度：
  1.000±0.06 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  23
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING
  申请人：Bulawa Christine

  公开号：US20100305068A1

  公开（公告）日：2010-12-02

  Disclosed are compositions and methods for modulating protein trafficking and treating or preventing disorders characterized by impaired protein trafficking. Also disclosed are methods for producing a protein and identifying compounds that rescue protein trafficking defects.
• THERAPEUTIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND USES THEREOF
  申请人：Meretzki Shai

  公开号：US20110217251A1

  公开（公告）日：2011-09-08

  Therapeutic compositions comprising pharmaceutically effective amounts of isolated polyhydroxylated fatty alcohols, in particular suitable for topical or systemic administration. A method for the isolation of a natural polyhydroxylated fatty alcohol from a fruit or vegetable source is also disclosed.
• COSMETIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOLS AND DERIVATIVES AND USES THEREOF
  申请人：Meretzki Shai

  公开号：US20110250154A1

  公开（公告）日：2011-10-13

  Cosmetic methods and compositions for preventing or reversing damage caused to the skin of a subject by environmental pollution and/or UV radiation, the methods and compositions comprising isolated polyhydroxylated fatty alcohols or derivatives thereof for topical application, in an amount effective to prevent or reverse the harmful effects of environmental pollution and/or UV radiation on the skin e.g. by reducing the damage to the skin cells and/or improving the aesthetic appearance of human skin.
• Chemosensory Receptor Ligand-Based Therapies
  申请人：Baron Alain D.

  公开号：US20130281387A1

  公开（公告）日：2013-10-24

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
• AVOCADO-DERIVED LIPIDS FOR USE IN TREATING LEUKEMIA
  申请人：SPAGNUOLO Paul Anthony

  公开号：US20170304251A1

  公开（公告）日：2017-10-26

  A method of treating a leukemia comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a compound of Formula (I) and/or (II) having the structure: OR2 R R1O n OR2 R R1O n I II wherein: 10 ---- represents a single or a double bond; R is OH when C----R is C—R, and R is O when C----R is C═R; n is 1, 3, 5 or 7; and R1 and R2 are independently hydrogen or acetyl, and/or isomers, stereoisomers or solvates thereof and/or mixtures thereof.