1-(2,3-Epoxypropyl)-succinimide | 20958-21-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-(2,3-Epoxypropyl)-succinimide
• 英文别名: 1-(2,3-epoxypropyl)-2,5-pyrrolidinedione；N-(2,3-Epoxy-propyl)-succinimid；1-(Oxiran-2-ylmethyl)pyrrolidine-2,5-dione
• CAS: 20958-21-8
• 化学式: C₇H₉NO₃
• mdl: MFCD00460358
• 分子量: 155.153
• InChiKey: QVNQWADZKGITKV-UHFFFAOYSA-N

物化性质

• 熔点：
  52 °C
• 沸点：
  322.6±15.0 °C(Predicted)
• 密度：
  1.401±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.714
• 拓扑面积：
  49.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(2,3-Epoxypropyl)-succinimide 在 chromium(VI) oxide 、 盐酸 、 硫酸 、 三乙胺 作用下， 以 氯仿 、 丙酮 、 乙腈 为溶剂， 反应 1.5h， 生成 1-[2-Oxo-3-(4-o-tolyl-piperazin-1-yl)-propyl]-pyrrolidine-2,5-dione
  参考文献：
  名称：

  Khadilkar, B M; Bhayade, S R, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1993, vol. 32, # 3, p. 338 - 342

  摘要：

  DOI：
• 作为产物：
  描述：

  potassium succinimide 、 环氧氯丙烷 以 乙腈 为溶剂， 反应 6.0h， 以37%的产率得到1-(2,3-Epoxypropyl)-succinimide
  参考文献：
  名称：

  用Olah试剂在甲基上带有吸电子取代基的环氧丙烷的开环区域选择性

  摘要：

  Olah试剂（Py·9HF）对末端环氧化物进行氢氟化的区域化学反应取决于β取代基的吸电子特性。研究了具有不同取代模式的芳环和几个N杂环的苯氧基醚作为β取代基。

  DOI：

  10.1016/s0022-1139(98)00270-x

文献信息

• 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives
  申请人：Miki Yasushi

  公开号：US20060019993A1

  公开（公告）日：2006-01-26

  An 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivative represented by the following formula (1), wherein cycle A may have further 1 to 4 substituents, and said substituent means a substituent selected from the group consisting of saturated or unsaturated C1-4 alkyl group, aralkyl group in which alkyl moiety has 1 to 4 carbon atoms, aryl group, halogen atom, halogenated C1-4 alkyl group, C2-5 alkanoyl group, mono or dialkylcarbamoyl group in which alkyl moiety has 1 to 4 carbon atoms, cyano group and nitro group, and the substituents at positions 3 and 6, or at positions 4 and 5 on the cycle A are different each other. Other ring may be fused at positions 3 and 4, or at positions 5 and 6 on the cycle A to form a condensed polycyclic hydrocarbon with the cycle A. R 1 is alkanoyl group or aroyl group, and R 2 is hydrogen atom, alkanoyl group or aroyl group, or R 1 and R 2 may be combined together with the N atom to form a cyclic imido group, which is useful as an intermediate of medicines, etc.

  由以下公式（1）表示的1-酰胺-3-(2-羟基苯氧基)-2-丙醇衍生物，其中环A可能有进一步的1到4个取代基，所述取代基是从饱和或不饱和的C1-4烷基，含有1到4个碳原子的芳基烷基，芳基，卤素原子，卤代C1-4烷基，C2-5烷酰基，单或二烷基氨基基，其中烷基部分含有1到4个碳原子，氰基和硝基中选择的取代基，并且在环A上的位置3和6，或在位置4和5上的取代基彼此不同。其他环可能在环A上的位置3和4，或在位置5和6上与环A融合，形成与环A的紧缩多环碳氢化合物。R1是烷酰基或芳酰基，R2是氢原子，烷酰基或芳酰基，或R1和R2可以与N原子结合在一起形成环亚胺基团，可用作药物等的中间体。
• Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters
  申请人：TEIJIN LIMITED

  公开号：EP0019061A1

  公开（公告）日：1980-11-26

  A process for producing an aromatic polyester having an increased degree of polymerization. The process comprises reacting a hydroxyl-terminated, substantially linear, fiber-forming aromatic polyester having an aromatic dicarboxylic acid as a main acid component at an elevated temperature with a bi-cyclic imino ester compound of formula (I) or formula (II). According to the process, the molecularchains of the aromatic polyester are bonded to each other by the terminal hydroxyl groups thereof to form rapidly the aromatic polyester having an increased degree of polymerization. I Bis-oxazolones 11 Bis-oxazinones e.g.

  一种生产聚合度提高的芳香族聚酯的工艺。该工艺包括在高温下使以芳香族二羧酸为主要酸组分的羟基封端、基本线性的芳香族聚酯与式 (I) 或式 (II) 的双环亚氨基酯化合物反应。根据该工艺，芳香族聚酯的分子链通过其末端羟基相互键合，从而快速形成聚合度提高的芳香族聚酯。 I 双噁唑酮 11 双噁唑酮，例如
• RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1445282A1

  公开（公告）日：2004-08-11

  Disclosed are a resin composition comprising a polylactic acid resin and a polyacetal resin, and such a resin composition in which the polylactic acid resin and the polyacetal resin are kept miscible with each other. The resin composition has good moldability, workability, mechanical properties, heat resistance and transparency, and may be worked into moldings, films and fibers for practical use.

  本发明公开了一种由聚乳酸树脂和聚缩醛树脂组成的树脂组合物，以及聚乳酸树脂和聚缩醛树脂保持互溶的树脂组合物。该树脂组合物具有良好的成型性、加工性、机械性能、耐热性和透明性，可加工成模塑件、薄膜和纤维以供实际使用。
• ALIPHATIC POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, MOLDED ARTICLE AND FOAMED ARTICLE COMPRISING THE RESIN COMPOSITION
  申请人：UNITIKA LTD.

  公开号：EP1640406A1

  公开（公告）日：2006-03-29

  An aliphatic polyester resin composition is provided which is excellent in heat resistance, moldability and hydrolysis resistance. The aliphatic polyester resin composition comprises a biodegradable polyester resin (A) essentially including an α- and/or β-hydroxycarboxylic acid unit and crosslinked by at least one crosslinking agent (B) selected from the group consisting of (meth)acrylate compounds and polyvalent isocyanate compounds, wherein some or all of carboxyl groups of the resin (A) are blocked by 0.01 to 20 parts by mass of a terminal blocking agent (C) based on 100 parts by mass of the resin (A).

  一种脂肪族聚酯树脂组合物具有优异的耐热性、成型性和抗水解性。脂肪族聚酯树脂组合物包括一种可生物降解的聚酯树脂（A），主要包括一个α-和/或β-羟基羧酸单元，并通过至少一种交联剂（B）交联，交联剂（B）选自（甲基）丙烯酸酯化合物和多价异氰酸酯化合物组成的组，其中树脂（A）的部分或全部羧基被 0.01 至 20 质量份的末端封端剂（C）封端（以 100 质量份的树脂（A）为基准）。
• RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1903077A1

  公开（公告）日：2008-03-26

  A resin composition comprising a polylactic acid-based resin (A) and methacrylic resins (B), wherein the methacrylic resins having at least (a) a difference of 10°C or more in glass transition temperature or (b) a difference of 3% or more in syndiotacticity; it is preferred that at least one of the methacrylic resins (B) is a methacrylic resin having a weight average molecular weight of 50,000 to 450,000, a glass transition temperature of 110°C or higher and a syndiotacticity of 40% or more, and that the resin composition further contains a multilayer structure polymer formed as particles each consisting of a core layer and one or more shell layers covering it (C). A molded article made of said resin composition.

  一种树脂组合物，包括聚乳酸基树脂（A）和甲基丙烯酸树脂（B），其中甲基丙烯酸树脂至少(a)在玻璃化转变温度上相差 10°C 或更多，或(b)在联合活度上相差 3% 或更多；优选至少一种甲基丙烯酸树脂 (B) 是重量平均分子量为 50,000 至 450,000 的甲基丙烯酸树脂，玻璃化温度为 110°C 或更高，辛二酸度为 40% 或更高，并且该树脂组合物还包含一种多层结构聚合物，该聚合物形成为颗粒，每个颗粒由芯层和覆盖在芯层上的一层或多层壳层组成 (C)。由所述树脂组合物制成的模塑制品。