4-Phenoxy-1-methyl-cyclohexan | 92035-69-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-Phenoxy-1-methyl-cyclohexan
• 英文别名: 4-Phenoxy-methylcyclohexan；4-Methylcyclohexyl phenyl ether；(4-methylcyclohexyl)oxybenzene
• CAS: 92035-69-3
• 化学式: C₁₃H₁₈O
• 分子量: 190.285
• InChiKey: DOSJSHWAHRWSBY-UHFFFAOYSA-N

物化性质

• 沸点：
  95 °C(Press: 2.5 Torr)
• 密度：
  0.9840 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-甲基环己醇 在 硫酸 、 氢溴酸 作用下， 生成 4-Phenoxy-1-methyl-cyclohexan
  参考文献：
  名称：

  Vinyl compounds in the diene synthesis

  摘要：

  DOI：

  10.1007/bf00908401

文献信息

• Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
  申请人：——

  公开号：US20030229136A1

  公开（公告）日：2003-12-11

  Novel compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) 1 wherein R 1 through R 3 and R 5 through R 11 are defined herein, and &agr;, &bgr; and &ggr; are optional bonds, providing that when &agr; is absent, &bgr; is present, and when &bgr; is absent, &agr; is present. When &agr; is present, preferred R 4 moieties are selected from O, S, NH and CH 2 , and when &agr; is absent, preferred R 4 groups are selected from OH, SH, NH 2 and CH 3 . When &ggr; is present, the preferred R 5 substituent is O, while when &ggr; is absent, the preferred R 5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.

  提供了作为化疗、化学预防和抗血管生成的有用化合物。这些化合物是类黄酮类化合物，包括黄酮酮、黄烷醇和香豆素。这些化合物具有公式（I）的结构，其中R1至R3和R5至R11在此定义，α、β和γ为可选键，当α不存在时，β存在，当β不存在时，α存在。当α存在时，首选的R4基团从O、S、NH和CH2中选择，当α不存在时，首选的R4基团从OH、SH、NH2和CH3中选择。当γ存在时，首选的R5取代基是O，而当γ不存在时，首选的R5取代基是OH。还提供了药物组合物，以及合成和使用方法。
• Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
  申请人：——

  公开号：US20040192723A1

  公开（公告）日：2004-09-30

  Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of polyphenol catechins that occur in green tea, such as epigallocatichin-3-gallate (EGCG), and have the structure of formula (I) 1 wherein R 1 through R 11 are defined herein. Preferred R 4 moieties are selected from O, S, NH and CH 2 , and in exemplary compounds, R 4 is O and R 5 is a tri-substituted aroyloxy substituent, such as a 3,4,5-substituted benzoyloxy group. Pharmaceutical compositions are provided as well, as are methods of chemotherapy and chemoprevention.

  提供了作为化疗和化学预防剂有用的新化合物。这些化合物是绿茶中存在的多酚儿茶素的类似物，例如表儿茶素-3-没食子酸酯（EGCG），并具有以下结构的公式（I）其中R1至R11在此处定义。首选的R4基团从O、S、NH和CH2中选择，在示例化合物中，R4为O，R5为三取代芳酰氧基取代物，例如3,4,5-取代苯甲酰氧基基团。还提供了药物组合物，以及化疗和化学预防的方法。
• FUNGICIDAL COMPOSITIONS
  申请人：Haas Ulrich Johannes

  公开号：US20140335201A1

  公开（公告）日：2014-11-13

  The present invention provides a composition comprising a combination of components A) and B), wherein component A) is a compound of formula (I) and the component (B) is a further fungicide, insecticide or herbicide.

  本发明提供了一种组合物，包括组分A)和B)，其中组分A)是化合物的公式(I)，组分B)是另一种杀真菌剂、杀虫剂或除草剂。
• NOVEL FLAVANOIDS AND CHALCONES AS CHEMOTHERAPEUTIC, CHEMOPREVENTIVE, AND ANTIANGIOGENIC AGENTS
  申请人：Sri International

  公开号：EP1495014A2

  公开（公告）日：2005-01-12
• FLAVANOIDS DERIVATIVES AS CHEMOTHERAPEUTIC, CHEMOPREVENTIVE, AND ANTIANGIOGENIC AGENTS
  申请人：SRI International

  公开号：EP1495014B1

  公开（公告）日：2009-07-29