7-(diethylamino)-2-oxo-N-(5-oxo-5-((2,2,6,6-tetramethylpiperidin-4-yl)amino)pentyl)-2H-chromene-3-carboxamide | 1451059-35-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 7-(diethylamino)-2-oxo-N-(5-oxo-5-((2,2,6,6-tetramethylpiperidin-4-yl)amino)pentyl)-2H-chromene-3-carboxamide
• 英文别名: 7-(diethylamino)-2-oxo-N-[5-oxo-5-[(2,2,6,6-tetramethylpiperidin-4-yl)amino]pentyl]chromene-3-carboxamide
• CAS: 1451059-35-0
• 化学式: C₂₈H₄₂N₄O₄
• 分子量: 498.666
• InChiKey: JPCRAOXQGMNKTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  36
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  99.8
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  7-(二乙基氨基)香豆素-3-羧酸 在 N-甲基吗啉 、 盐酸 、 水 、 O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 作用下， 以 1,4-二氧六环 、 二氯甲烷 为溶剂， 反应 30.0h， 生成 7-(diethylamino)-2-oxo-N-(5-oxo-5-((2,2,6,6-tetramethylpiperidin-4-yl)amino)pentyl)-2H-chromene-3-carboxamide
  参考文献：
  名称：

  Coumarin-based dual fluorescent spin-probes

  摘要：

  New, dual profluorescent spin-probes and their fluorescent amine analogues, as potential spin traps, have been synthesized and characterized. Comparison between the fluorescence spectra of amines and their corresponding nitroxides established spacer distance dependent quenching of fluorescence. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.07.084

文献信息

• Coumarin-based dual fluorescent spin-probes
  作者：Janez Mravljak、Tadej Ojsteršek、Stane Pajk、Marija Sollner Dolenc

  DOI：10.1016/j.tetlet.2013.07.084

  日期：2013.9

  New, dual profluorescent spin-probes and their fluorescent amine analogues, as potential spin traps, have been synthesized and characterized. Comparison between the fluorescence spectra of amines and their corresponding nitroxides established spacer distance dependent quenching of fluorescence. (C) 2013 Elsevier Ltd. All rights reserved.