2-(N-allyl)aminothiophenol | 66779-96-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: 2-(N-allyl)aminothiophenol
• 英文别名: 2-allylamino-benzenethiol；2-allylamino-thiophenol；2-(Prop-2-enylamino)benzenethiol
• CAS: 66779-96-2
• 化学式: C₉H₁₁NS
• 分子量: 165.259
• InChiKey: RRZSJKJFDQZALK-UHFFFAOYSA-N

物化性质

• 沸点：
  112-115 °C(Press: 3 Torr)
• 密度：
  1.104±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  13
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(N-allyl)aminothiophenol 以72%的产率得到
  参考文献：
  名称：

  FENNER H.; GRAUERT R. W., ARCH. PHARM. , 1978, 311, NO 4, 303-310

  摘要：

  DOI：
• 作为产物：
  描述：

  2-氨基苯基苯甲基硫代醚 在 sodium hydroxide 、 titanium(III) chloride 、 lithium 、 potassium carbonate 作用下， 以 四氢呋喃 、 乙醇 、 苯 为溶剂， 反应 86.0h， 生成 2-(N-allyl)aminothiophenol
  参考文献：
  名称：

  Shadakshari; Talukdar; Chattopadhyay, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001, vol. 40, # 10, p. 1007 - 1010

  摘要：

  DOI：

文献信息

• Photosensitive polyfunctional aromatic diazo compounds and photosensitive compositions using the same
  申请人：TOYO GOSEI KOGYO CO., LTD.

  公开号：EP0580121A2

  公开（公告）日：1994-01-26

  An aromatic diazo compound is composed mainly of a compound of Formula (I) or Formula (II), and a photosensitive composition using the same. The aromatic diazo compound can be handled under a white light, is highly photosensitive, has good shelf life, is highly soluble in organic solvents, adequate as a photosensitive agent for lithographic printing plates, can be easily developed with a developing solution composed mainly of an alkaline aqueous solution, and has an appropriate water solubility as a screen printing plate: Formula (I) wherein ℓ, m, and n are integers where ℓ = 2 to 10, m = 0 to 5, n = 0 to 5, and ℓ + m + n = 2 to 20. R1 and R2 are independently hydrogen, or alkyl or alkyloxy of 1 to 8 carbon atoms; G1 is a substituent derived from alcoholic hydroxyl group; G2 is hydroxyl or the same group as G1; Q is a polyvalent group generated by reacting a compound having a reactivity to at least two oxiranes with carbon of the oxirane ring; Q1 is a monovalent group generated by reacting a compound having a reactivity to oxirane with carbon of the oxirane ring; R3 is alkyl or substituted alkyl of 1 to 8 carbon atoms, aralkyl or substituted aralkyl of 7 to 14 carbon atoms, or Q1-CH2CHG2-CH2-; X- is an anion based on protonic acid from which a proton is removed. Formula (II) wherein n1 to n' are integers from 0 to 10; n1 + n2 + n3 + ... + ni = 2 to 20; R1, R2, R3 and X- are respectively the same as those in Formula (I); G2 is hydroxyl or the same group as G1 in Formula (I), and the number of hydroxyl groups represented by G2 in one molecule of a diazo compound of Formula (II) is 0 to 10, and the number of groups same as G1 is 2 to 20; Q21 to Q2i and Qs are the same or two or more different groups, and are divalent groups generated by reacting a compound which one molecule being reactable with two oxirane rings with carbons of two oxirane rings; R4 is the same as Q1 or G2 in Formula (I), or Formula (III). Formula (III) wherein X-, R1, R2, and R3 are the same as in Formula (I).

  一种芳香重氮化合物主要由式（I）或式（II）化合物和使用该化合物的感光组合物组成。该芳香重氮化合物可在白光下处理，光敏性强，保存期长，在有机溶剂中的溶解度高，适于作为平版印刷版的感光剂，易于用主要由碱性水溶液组成的显影液显影，作为丝网印版具有适当的水溶性：式（I） 其中 ℓ、m、n 为整数，ℓ = 2 至 10，m = 0 至 5，n = 0 至 5，ℓ + m + n = 2 至 20。 R1 和 R2 独立地为氢、1 至 8 个碳原子的烷基或烷氧基； G1 是由醇羟基衍生的取代基； G2 是羟基或与 G1 相同的基团； Q 是多价基团，通过与至少两个环氧乙烷具有反应活性的化合物与环氧乙烷环的碳反应生成； Q1 是一个单价基团，通过与环氧乙烷具有反应活性的化合物反应生成； R3 是 1 至 8 个碳原子的烷基或取代烷基、7 至 14 个碳原子的芳基或取代芳基或 Q1-CH2CHG2-CH2-； X- 是基于质子酸的阴离子，其中一个质子被去除。式 (II) 其中 n1 至 n' 为 0 至 10 的整数； n1 + n2 + n3 + ...+ ni = 2 至 20；R1、R2、R3 和 X- 分别与式（I）中的相同； G2 是羟基或与式(I)中 G1 相同的基团，在一个分子的式(II)重氮化合物中，G2 所代表的羟基数目为 0 至 10，与 G1 相同的基团数目为 2 至 20； Q21 至 Q2i 和 Qs 是相同的基团或两个或两个以上不同的基团，并且是二价基团，由一个分子可与两个环氧乙烷环反应的化合物与两个环氧乙烷环的碳反应生成； R4 与式（I）或式（III）中的 Q1 或 G2 相同。式 (III) 其中 X-、R1、R2 和 R3 与式（I）中的相同。
• Near infrared absorber, preparation process thereof and use thereof
  申请人：MITSUI TOATSU CHEMICALS, INCORPORATED

  公开号：EP0718375A2

  公开（公告）日：1996-06-26

  A phthalocyanine near infrared absorber having a broad absorption range in the near infrared region and represented by the following formula (1): wherein R¹ and R² each independently represents a hydrogen atom, a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group; Ys each independently represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkoxy group, or a substituted or unsubstituted aryloxy group; m stands for an integer of 0 to 4; Pc represents a phthalocyanine nucleus; Z represents an -SH group or an -NHR³ group in which R³ represents a hydrogen atom, a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group; Xs each independently represents a halogen atom, a hydroxy group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted aryloxy group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted arylthio group, a substituted or unsubstituted alkylamino group, a substituted or unsubstituted arylamino group and a substituted or unsubstituted alkylarylamino group; the adjacent pairs of Xs may form a 5- or 6-membered ring via two hetero atoms; M represents a divalent metal atom, a substituted trivalent or tetravalent metal or an oxymetal atom; p stands for an integer of 1 to 16; q stands for an integer of 0 to 8; r stands for an integer of 0 to 8; and p + 2q + r is not greater than 16.

  一种酞菁近红外吸收剂，在近红外区域具有宽广的吸收范围，由下式（1）表示： 其中 R¹ 和 R² 各自独立地代表氢原子、取代或未取代的烷基或取代或未取代的芳基； Ys 各自独立地代表取代或未取代的烷基、取代或未取代的芳基、取代或未取代的烷氧基或取代或未取代的芳氧基；m 代表 0 至 4 的整数； Pc 代表酞菁核； Z 代表-SH 基团或-NHR³ 基团，其中 R³ 代表氢原子、取代或未取代的烷基或取代或未取代的芳基；Xs 各自独立地代表卤原子、羟基、取代或未取代的烷氧基、取代或未取代的芳氧基、取代或未取代的烷硫基、取代或未取代的芳硫基、取代或未取代的烷基氨基、取代或未取代的芳基氨基和取代或未取代的烷基芳基氨基；相邻的 Xs 对可通过两个杂原子形成 5 或 6 元环； M 代表二价金属原子、取代的三价或四价金属或氧金属原子； p 代表 1 至 16 的整数； q 代表 0 至 8 的整数； r 代表 0 至 8 的整数；且 p + 2q + r 不大于 16。
• Process for preparing optically active 2-halogeno-3-hydroxypropionic acid ester
  申请人：TANABE SEIYAKU CO., LTD.

  公开号：EP0808824A2

  公开（公告）日：1997-11-26

  A novel process for preparing optically active 2-halogeno-3-hydroxypropionic acid ester compound (III), which comprises reacting the aldehyde compound (I) with the silylketene acetal compound (II) in the presence of a chiral Lewis acid, as illustrated below. wherein R is aryl, cycloalkyl, etc., one of X1 and X2 is H, and the other is Cl or Br, or both are Cl or Br, R1, R2 and R3 are the same or different, and are lower alkyl or aryl, R4 is lower alkyl or aryl, and * is asymmetric carbon atom. The compound (III) is very useful as an intermediate for preparing medicament such as diltiazem hydrochloride.

  一种制备光学活性 2-卤代-3-羟基丙酸酯化合物(III)的新工艺，包括在手性路易斯酸存在下，使醛化合物(I)与硅酮缩醛化合物(II)反应，如下图所示。 其中 R 为芳基、环烷基等，X1 和 X2 中的一个为 H，另一个为 Cl 或 Br，或两者均为 Cl 或 Br，R1、R2 和 R3 相同或不同，且为低级烷基或芳基，R4 为低级烷基或芳基，* 为不对称碳原子。化合物（III）作为制备盐酸地尔硫卓等药物的中间体非常有用。
• Anthelmintic quaternary salts. III. Benzothiazolium salts
  作者：David L. Garmaise、Gerard Y. Paris、Jacqueline Komlossy、C. H. Chambers、R. C. McCrae

  DOI：10.1021/jm00301a008

  日期：1969.1
• Verfahren zur Herstellung von Dihydroxyaceton
  申请人：BASF Aktiengesellschaft

  公开号：EP0526737B1

  公开（公告）日：1995-03-15