(S)-6,6'-bi(5-chrysenol)

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: (S)-6,6'-bi(5-chrysenol)
• 英文别名: 6-(5-Hydroxychrysen-6-yl)chrysen-5-ol；6-(5-hydroxychrysen-6-yl)chrysen-5-ol
• 化学式: C₃₆H₂₂O₂
• 分子量: 486.569
• InChiKey: CPIVFOYDUMLRRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.3
• 重原子数：
  38
• 可旋转键数：
  1
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  chrysen-5-ol 在 (Ra,S,S)-(C₁₀H₉(VO₂(OH))(CHNCH(C(CH₃)3)COO))2 、 氧气 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以55%的产率得到(S)-6,6'-bi(5-chrysenol)
  参考文献：
  名称：

  Enantioselective oxidative-coupling of polycyclic phenols

  摘要：

  Enantioselective oxidative-coupling of polycyclic phenols, such as 2-anthracenol, 9- or 3-phenanthrol, and 5-chrysenol was established by using vanadium(V/IV) catalysis under air or 02 as a co-oxidant. In the vanadium catalyzed reaction, the corresponding coupling products were obtained in good to excellent yields with up to 93% enantiomeric excess. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.01.017

文献信息

• Enantioselective oxidative-coupling of polycyclic phenols
  作者：Shinobu Takizawa、Junpei Kodera、Yasushi Yoshida、Makoto Sako、Stefanie Breukers、Dieter Enders、Hiroaki Sasai

  DOI：10.1016/j.tet.2014.01.017

  日期：2014.3

  Enantioselective oxidative-coupling of polycyclic phenols, such as 2-anthracenol, 9- or 3-phenanthrol, and 5-chrysenol was established by using vanadium(V/IV) catalysis under air or 02 as a co-oxidant. In the vanadium catalyzed reaction, the corresponding coupling products were obtained in good to excellent yields with up to 93% enantiomeric excess. (C) 2014 Elsevier Ltd. All rights reserved.