4-phenylindan | 83846-26-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 4-phenylindan
• 英文别名: 7-phenylindane；4-phenyl-2,3-dihydro-1H-indene
• CAS: 83846-26-8
• 化学式: C₁₅H₁₄
• 分子量: 194.276
• InChiKey: KUMDVQUAWVXWHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4-phenylindan 在 potassium permanganate 作用下， 以 sodium hydroxide 为溶剂， 生成 biphenyl-2,3-dicarboxylic acid
  参考文献：
  名称：

  Dehydration of 1-substituted secondary and tertiary bicyclo[3.3.1]nonan-9-ols. A substituent-driven rearrangement to 4-substituted and/or angularly substituted hexahydroindenes

  摘要：

  DOI：

  10.1021/jo00152a030
• 作为产物：
  描述：

  [(1E)-4-溴-1-丁烯-1-基]苯 在 dilithium tetrachlorocuprate 、 magnesium 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 苯 为溶剂， 反应 49.0h， 生成 4-phenylindan
  参考文献：
  名称：

  The triplex Diels-Alder reaction: intramolecular cycloaddition of phenyl-substituted alkenes to 1,3-dienes

  摘要：

  The triplex Diels-Alder reaction of dienes and styrene-like dienophiles that are covalently linked with a flexible alkyl chain was investigated. Sensitization with 9,10-dicyanoanthracene in benzene solution leads to good yields of [4 + 2] adducts when the diene is a derivative of cyclohexadiene and the linking chain contains two atoms. If the linking chain contains three atoms, dyotropic transfer of hydrogens occurs. When acyclic dienes are employed, it is believed that conformational isomers lead to mixtures containing considerable yields of both [4 + 2] and [2 + 2] cycloadducts.

  DOI：

  10.1021/jo00026a023

文献信息

• Gold(<scp>i</scp>)-catalyzed dehydrogenative cycloisomerization of 1,5-enynes
  作者：Gen-Qiang Chen、Wei Fang、Yin Wei、Xiang-Ying Tang、Min Shi

  DOI：10.1039/c6cc05423d

  日期：——

  Gold(I)-catalyzed dehydrogenative cycloisomeriaztion of cyclopropane tethered 1,5-enynes proceeded smoothly to give multisubstituted benzene derivatives in good to excellent yields. Synthetically important benzocyclobutenes can be produced in high yields in the...

  金（I）催化的环丙烷束缚的1，5-炔烃的脱氢环异构化反应顺利进行，得到了多取代苯衍生物，收率很好。具有重要合成意义的苯并环丁烯可以在...
• The triplex Diels-Alder reaction: intramolecular cycloaddition of phenyl-substituted alkenes to 1,3-dienes
  作者：Ingrid Wolfle、Samantha Chan、Gary B. Schuster

  DOI：10.1021/jo00026a023

  日期：1991.12

  The triplex Diels-Alder reaction of dienes and styrene-like dienophiles that are covalently linked with a flexible alkyl chain was investigated. Sensitization with 9,10-dicyanoanthracene in benzene solution leads to good yields of [4 + 2] adducts when the diene is a derivative of cyclohexadiene and the linking chain contains two atoms. If the linking chain contains three atoms, dyotropic transfer of hydrogens occurs. When acyclic dienes are employed, it is believed that conformational isomers lead to mixtures containing considerable yields of both [4 + 2] and [2 + 2] cycloadducts.
• Dehydration of 1-substituted secondary and tertiary bicyclo[3.3.1]nonan-9-ols. A substituent-driven rearrangement to 4-substituted and/or angularly substituted hexahydroindenes
  作者：Fabrizio Balata、Anna R. Dello Jacono、Augusto Gambacorta

  DOI：10.1021/jo00152a030

  日期：1983.2