3,3-二甲基丁基(二苯基)膦 | 15672-89-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3,3-二甲基丁基(二苯基)膦
• 英文名称: (3,3-Dimethylbutyl)(diphenyl)phosphane
• 英文别名: 3,3-dimethylbutyl(diphenyl)phosphane
• CAS: 15672-89-6
• 化学式: C₁₈H₂₃P
• 分子量: 270.354
• InChiKey: CHUBDMDLPFIHPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  3,3-二甲基丁基(二苯基)膦 在 双氧水 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以60%的产率得到(3,3-dimethylbutyl)diphenylphosphine oxide
  参考文献：
  名称：

  以酰基膦为磷源的钯催化的C（sp 3）–P（III）键形成反应

  摘要：

  开发了钯催化的C（sp 3）–P（III）键形成烷基取代的膦的制备反应。在该反应中，各种烷基溴化物和有限的烷基氯化物在相对温和且易于获得的条件下与酰基膦反应，并以高收率获得了不同的膦。该反应弥补了钯催化在C（sp 3）–P（III）键形成中的应用，并表明了酰基膦作为磷化试剂的实际应用。

  DOI：

  10.1016/j.tetlet.2020.152125
• 作为产物：
  描述：

  二苯基膦 在 二(氰基苯)二氯化钯 、 caesium carbonate 、 三乙胺 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 36.0h， 生成 3,3-二甲基丁基(二苯基)膦
  参考文献：
  名称：

  以酰基膦为磷源的钯催化的C（sp 3）–P（III）键形成反应

  摘要：

  开发了钯催化的C（sp 3）–P（III）键形成烷基取代的膦的制备反应。在该反应中，各种烷基溴化物和有限的烷基氯化物在相对温和且易于获得的条件下与酰基膦反应，并以高收率获得了不同的膦。该反应弥补了钯催化在C（sp 3）–P（III）键形成中的应用，并表明了酰基膦作为磷化试剂的实际应用。

  DOI：

  10.1016/j.tetlet.2020.152125

文献信息

• [EN] HOMOGENEOUS PROCESS FOR THE HYDROGENATION OF DICARBOXYLIC ACIDS AND/OR ANHYDRIDES THEREOF<br/>[FR] PROCEDE HOMOGENE D'HYDROGENATION D'ACIDES DICARBOXYLIQUES ET/OU D'ANHYDRIDES DE CEUX-CI
  申请人：DAVY PROCESS TECHN LTD

  公开号：WO2005051875A1

  公开（公告）日：2005-06-09

  A homogeneous process for the hydrogenation of dicarboxylic acids and/or anhydrides in the presence of a catalyst comprising: (a) ruthenium, rhodium, iron, osmium or palladium; and (b) an organic phosphine; wherein the hydrogenation is carried out in the presence of at least about 1 % by weight water and wherein the reaction is carried out at a pressure. of from about 500 psig to about 2000 psig and a temperature of from about 200 °C to about 3OO °C such that from about 1 mol to about 10 mol of hydrogen are used to strip 1 mole of product from the reactor.

  一种均相过程，用于在催化剂的存在下氢化二羧酸和/或酐，所述催化剂包括：（a）钌、铑、铁、锇或钯；和（b）有机膦；其中氢化在至少约1%重量的水存在下进行，并且反应在约500 psig至约2000 psig的压力和约200°C至约300°C的温度下进行，使得约1摩尔至约10摩尔的氢用于从反应器中剥离1摩尔的产物。
• Polysilylated Organosilane Compounds
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

  公开号：US20150218192A1

  公开（公告）日：2015-08-06

  The invention concerns a mono- or polyfunctional polysilylated organosilane compound, and the method for preparing same.

  本发明涉及一种单官能或多官能的聚硅烷化有机硅化合物及其制备方法。
• Homogeneous and Heterogeneous Pd-Catalyzed Selective C–P Activation and Transfer Hydrogenation for “Group-Substitution” Synthesis of Trivalent Phosphines
  作者：Ming Lei、Xingyu Chen、Yingjie Wang、Liran Zhang、Hong Zhu、Zhiqian Wang

  DOI：10.1021/acs.orglett.2c00844

  日期：2022.4.22

  reported. The alkyl groups were introduced by alkylation of phosphines to form phosphonium salts. The “de-arylation” of phosphonium salts was achieved by C–P activation and transfer hydrogenation with homogeneous or heterogeneous Pd (0) catalysts. With this method, a series of trivalent phosphines were prepared from commercially available triarylphosphines. A chiral monophosphine ligand could be prepared

  报道了通过鏻盐的 C-P 活化合成三价膦的“基团取代”。通过膦的烷基化引入烷基以形成鏻盐。鏻盐的“去芳基化”是通过 C-P 活化和使用均相或非均相 Pd (0) 催化剂的转移氢化来实现的。采用这种方法，从市售的三芳基膦中制备了一系列三价膦。手性单膦配体可以从 BINAP 在“脱膦”过程中制备。
• Transition metal complex catalysts
  申请人：Exxon Research and Engineering

  公开号：US04668809A1

  公开（公告）日：1987-05-26

  Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group includes heteroorganic radicals containing ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups. These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce moslty aldehydes derived from terminal attack on the alpha-olefin reactant. In the case of low olefins, such as butene-1, the products can be advantageously removed in a continuous manner, as distillate components from a ligand reaction mixture kept at an elevated temperature and continuously fed by an appropriate mixture of the reactants.

  本发明披露了一种在氢甲酰化过程中非常有用的物质组成物。该组成物是非带电、非螯合的双(烷基二芳基膦)、三(烷基二芳基膦)铑羰基氢化物。烷基基团的取代基包括含有醚、酯、酮和羟基氧、膦氧和磷酸酯磷、胺、酰胺、胺氧和杂环氮基的杂有机基团。这些组成物是高度稳定和选择性的催化剂，可在一定条件下用于烯烃的氢甲酰化反应。披露的催化剂体系含有大量的膦配体，并采用具有高H.sub.2/CO比的α-烯烃加合物和合成气反应物混合物，在相对较低的压力下。它们主要产生从α-烯烃反应物的末端攻击中得到的醛。对于低烯烃，例如丁烯-1，可以从保持在高温下并由适当的反应物混合物连续供给的配体反应混合物中以馏分组分的形式优势地去除产物。
• Ligand exchange process for producing alkyl diaryl phosphine rhodium
  申请人：Exxon Research and Engineering Company

  公开号：US04687866A1

  公开（公告）日：1987-08-18

  Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group include heteroorganic radicals containing silane, silicone, ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups. These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce mostly aldehydes derived from terminal attack on the alpha-olefin reactant. In the case of low olefins, such as butene-1, the products can be advantageously removed in a continuous manner, as distillate components from a ligand reaction mixture kept at an elevated temperature and continuously fed by an appropriate mixture of the reactants.

  披露了在水合甲酰化过程中非常有用的物质组成物。这些组成物是非带电、非螯合的双(烷基二芳基膦)和三(烷基二芳基膦)铑羰基氢化物。烷基基团的取代基包括含有硅烷、硅氧烷、醚、酯、酮和羟基氧、膦氧和磷酸酯磷的杂有机基团、胺、酰胺、胺氧和杂环氮基团。这些组成物是高度稳定和选择性催化剂，在一定条件下用于烯烃的水合甲酰化反应。所披露的催化剂体系含有大量的膦配体，并使用具有高H.sub.2/CO比的α-烯烃和合成气反应物混合物，在相对较低的压力下。它们主要产生由α-烯烃反应物的末端攻击产生的醛。对于低烯烃，例如丁烯-1，可以从保持在高温下并由适当的反应物混合物连续供给的配体反应混合物中优势地连续地去除产物，作为馏分组分。