(2R,5S)-2-[(3E,5Z)-5-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methylhepta-3,5-dienyl]-5-(phenylsulfanylmethyl)-1,3-dioxolan-4-one | 200571-98-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (2R,5S)-2-[(3E,5Z)-5-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methylhepta-3,5-dienyl]-5-(phenylsulfanylmethyl)-1,3-dioxolan-4-one
• CAS: 200571-98-8
• 化学式: C₃₅H₄₂O₄SSi
• 分子量: 586.868
• InChiKey: CIEBHHZHIMZOJU-OQAOWFGISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  41
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  70.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (2R,5S)-2-[(3E,5Z)-5-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methylhepta-3,5-dienyl]-5-(phenylsulfanylmethyl)-1,3-dioxolan-4-one 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  An intramolecular Diels-Alder approach to the spirotetronic acid subunits of the quartromicins

  摘要：

  Three of the four diastereomeric spirotetronates (2, 19 and 24) corresponding to the quartromicins were synthesized by a sequence featuring the intramolecular Diels-Alder reaction of 3. An olefin isomerization pathway accounts for formation of the second most abundant cycloadduct, 16. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10415-4
• 作为产物：
  描述：

  (E)-5-iodo-4-methylpent-4-en-1-ol 在 盐酸 、 六甲基磷酰三胺 、 正丁基锂 、 三氟化硼乙醚 、 双(三甲基硅烷基)氨基钾 作用下， 以 四氢呋喃 为溶剂， 生成 (2R,5S)-2-[(3E,5Z)-5-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methylhepta-3,5-dienyl]-5-(phenylsulfanylmethyl)-1,3-dioxolan-4-one
  参考文献：
  名称：

  An intramolecular Diels-Alder approach to the spirotetronic acid subunits of the quartromicins

  摘要：

  Three of the four diastereomeric spirotetronates (2, 19 and 24) corresponding to the quartromicins were synthesized by a sequence featuring the intramolecular Diels-Alder reaction of 3. An olefin isomerization pathway accounts for formation of the second most abundant cycloadduct, 16. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10415-4

文献信息

• An intramolecular Diels-Alder approach to the spirotetronic acid subunits of the quartromicins
  作者：William R. Roush、David A. Barda

  DOI：10.1016/s0040-4039(97)10415-4

  日期：1997.12

  Three of the four diastereomeric spirotetronates (2, 19 and 24) corresponding to the quartromicins were synthesized by a sequence featuring the intramolecular Diels-Alder reaction of 3. An olefin isomerization pathway accounts for formation of the second most abundant cycloadduct, 16. (C) 1997 Elsevier Science Ltd.