3-aminooxypropanesulfonic acid | 357626-43-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 3-aminooxypropanesulfonic acid
• 英文别名: 3-Aminooxypropane-1-sulfonic acid
• CAS: 357626-43-8
• 化学式: C₃H₉NO₄S
• 分子量: 155.175
• InChiKey: DLCGEDYERACKNO-UHFFFAOYSA-N

物化性质

• 密度：
  1.455±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  98
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-甲氧基雌酮 、 3-aminooxypropanesulfonic acid 在 sodium acetate 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  ω-Aminooxyalkanesulfonic acids. Novel nucleophilic sulfoalkylation reagents

  摘要：

  Electrophilic sulfoalkylation reagents, such as 1,3-propanesultone, are widely used to enhance the hydrophilicity of polymers, proteins, etc. In this report, a series of nucleophilic sulfoalkylation reagents [NH2O(CH2)(n)SO3H, n = 2, 3, 4] were prepared from the corresponding chloroalkylsulfonyl chlorides. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00695-5
• 作为产物：
  描述：

  在 盐酸 、 水 作用下， 反应 1.5h， 以660 mg的产率得到3-aminooxypropanesulfonic acid
  参考文献：
  名称：

  ω-Aminooxyalkanesulfonic acids. Novel nucleophilic sulfoalkylation reagents

  摘要：

  Electrophilic sulfoalkylation reagents, such as 1,3-propanesultone, are widely used to enhance the hydrophilicity of polymers, proteins, etc. In this report, a series of nucleophilic sulfoalkylation reagents [NH2O(CH2)(n)SO3H, n = 2, 3, 4] were prepared from the corresponding chloroalkylsulfonyl chlorides. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00695-5

文献信息

• ω-Aminooxyalkanesulfonic acids. Novel nucleophilic sulfoalkylation reagents
  作者：Maciej Adamczyk、Yon-Yih Chen、Phillip G Mattingly

  DOI：10.1016/s0040-4039(01)00695-5

  日期：2001.6

  Electrophilic sulfoalkylation reagents, such as 1,3-propanesultone, are widely used to enhance the hydrophilicity of polymers, proteins, etc. In this report, a series of nucleophilic sulfoalkylation reagents [NH2O(CH2)(n)SO3H, n = 2, 3, 4] were prepared from the corresponding chloroalkylsulfonyl chlorides. (C) 2001 Elsevier Science Ltd. All rights reserved.