[4-[3,5-Bis[[3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methoxy]phenyl]-3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methanol | 350035-63-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-[3,5-Bis[[3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methoxy]phenyl]-3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methanol
• 英文别名: [4-[3,5-bis[[3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methoxy]phenyl]-3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methanol
• CAS: 350035-63-1
• 化学式: C₆₀H₉₀O₁₈
• 分子量: 1099.36
• InChiKey: CHOJYMQQQWTGFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  78
• 可旋转键数：
  50
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  177
• 氢给体数：
  1
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  [4-[3,5-Bis[[3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methoxy]phenyl]-3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methanol 在 四溴化碳 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 以69%的产率得到4-Bromomethyl-6-butoxy-3',5'-bis-(3-butoxy-5-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-benzyloxy)-2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-biphenyl
  参考文献：
  名称：

  Toward Globular Macromolecules with Functionalized Interiors:  Design and Synthesis of Dendrons with an Interesting Twist

  摘要：

  [GRAPHCIS]Design and synthesis of a novel class of monodendrons, in which the functional units can potentially be directed toward the concave interiors of dendrimers, are described. The key feature of the design is the placement of the amphiphilic and the AB(2) functional groups in orthogonal planes.

  DOI：

  10.1021/ol016064b
• 作为产物：
  描述：

  3,5-二羟基苯甲醇 在 18-冠醚-6 、 四溴化碳 、 potassium carbonate 、 三苯基膦 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 39.0h， 生成 [4-[3,5-Bis[[3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methoxy]phenyl]-3-butoxy-5-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]methanol
  参考文献：
  名称：

  Toward Globular Macromolecules with Functionalized Interiors:  Design and Synthesis of Dendrons with an Interesting Twist

  摘要：

  [GRAPHCIS]Design and synthesis of a novel class of monodendrons, in which the functional units can potentially be directed toward the concave interiors of dendrimers, are described. The key feature of the design is the placement of the amphiphilic and the AB(2) functional groups in orthogonal planes.

  DOI：

  10.1021/ol016064b

文献信息

• Toward Globular Macromolecules with Functionalized Interiors:  Design and Synthesis of Dendrons with an Interesting Twist
  作者：Pandi Bharathi、Hongda Zhao、S. Thayumanavan

  DOI：10.1021/ol016064b

  日期：2001.6.1

  [GRAPHCIS]Design and synthesis of a novel class of monodendrons, in which the functional units can potentially be directed toward the concave interiors of dendrimers, are described. The key feature of the design is the placement of the amphiphilic and the AB(2) functional groups in orthogonal planes.