1-butyl-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydropyridin-4-one | 1255704-42-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1-butyl-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydropyridin-4-one
• CAS: 1255704-42-7
• 化学式: C₂₃H₂₅NO₃
• 分子量: 363.456
• InChiKey: PCYCELFZPAZGKU-RUDMXATFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  双去甲氧基姜黄素 、 丁基铵乙酸盐 在 Montmorillonite K-10 作用下， 反应 0.02h， 以26%的产率得到1-butyl-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydropyridin-4-one
  参考文献：
  名称：

  Synthesis of novel 2,3-dihydro-4-pyridinones from bisdemethoxycurcumin under microwave irradiation

  摘要：

  A novel synthesis of 2,3-dihydro-4-pyridinones via the reaction of bisdemethoxycurcumin and primary amines or amine acetates is demonstrated. The structures of the products were established by elemental analysis and from mass, H-1 and C-13 NMR spectra. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.08.115

文献信息

• Synthesis of novel 2,3-dihydro-4-pyridinones from bisdemethoxycurcumin under microwave irradiation
  作者：Bahjat A. Saeed、Wisam A. Radhi、Rita S. Elias

  DOI：10.1016/j.tetlet.2010.08.115

  日期：2010.11

  A novel synthesis of 2,3-dihydro-4-pyridinones via the reaction of bisdemethoxycurcumin and primary amines or amine acetates is demonstrated. The structures of the products were established by elemental analysis and from mass, H-1 and C-13 NMR spectra. (C) 2010 Elsevier Ltd. All rights reserved.