(S)-2-Amino-4-{(R)-1-(carboxymethyl-carbamoyl)-2-[(E)-3-(3-hexyloxy-phenyl)-3-oxo-propenylsulfanyl]-ethylcarbamoyl}-butyric acid | 111651-83-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-Amino-4-{(R)-1-(carboxymethyl-carbamoyl)-2-[(E)-3-(3-hexyloxy-phenyl)-3-oxo-propenylsulfanyl]-ethylcarbamoyl}-butyric acid
• 英文别名: (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-[(E)-3-(3-hexoxyphenyl)-3-oxoprop-1-enyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
• CAS: 111651-83-3
• 化学式: C₂₅H₃₅N₃O₈S
• 分子量: 537.634
• InChiKey: NQOBTBUDOZDQDM-IALFWVKVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  37
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  210
• 氢给体数：
  5
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  3'-己氧基苯乙酮 在 甲醇 、 sodium hydride 、 甲基磺酰氯 、 三乙胺 作用下， 以 乙二醇二甲醚 为溶剂， 反应 25.0h， 生成 (S)-2-Amino-4-{(R)-1-(carboxymethyl-carbamoyl)-2-[(E)-3-(3-hexyloxy-phenyl)-3-oxo-propenylsulfanyl]-ethylcarbamoyl}-butyric acid
  参考文献：
  名称：

  Practical, stable standards for the reversed phase HPLC analysis of peptidic leukotrienes

  摘要：

  DOI：

  10.1016/s0040-4039(01)80976-x

文献信息

• Pigment dispersant with hindered light amine stabilizer and pigment dispersions and coating compositions based thereon
  申请人：PPG Industries Ohio, Inc.

  公开号：US10557045B2

  公开（公告）日：2020-02-11

  A pigment dispersion is disclosed comprising (a) at least one pigment and (b) a polymeric dispersant comprising residual units derived from polymerization of a mixture of monomers comprising (b1) at least one ethylenically unsaturated hindered amine light stabilizing monomer and (b2) at least one additional ethylenically unsaturated monomer different from monomer (b1). Coating compositions comprising the same are also disclosed as are substrates coated at least in part with such coatings.

  本发明公开了一种颜料分散剂，包括(a)至少一种颜料和(b)聚合物分散剂，聚合物分散剂由单体混合物聚合产生的残留单元组成，单体混合物包括(b1)至少一种乙烯基不饱和受阻胺光稳定单体和(b2)至少一种不同于单体(b1)的额外乙烯基不饱和单体。此外，还公开了包含上述成分的涂层组合物，以及至少部分涂有此类涂层的基材。
• Ethylenically unsaturated amine salts of sulfonic, phosphoric, and carboxylic acids
  申请人：Stepan Company

  公开号：US20010018461A1

  公开（公告）日：2001-08-30

  Disclosed are ethylenically unsaturated amine salts of sulfonic, phosphoric and carboxylic acids. The salts are surface active agents which are useful in a variety of applications as primary and/or secondary surfactants. The salts are especially useful as surfactants in emulsion polymerization reactions.

  本发明公开了磺酸、磷酸和羧酸的乙烯不饱和胺盐。这些盐类是表面活性剂，在各种应用中可用作一级和/或二级表面活性剂。这些盐在乳液聚合反应中作为表面活性剂尤其有用。
• Antimicrobial polymer latexes derived from unsaturated quaternary ammonium compounds and antimicrobial coatings, sealant, adhesives and elastomers produced from such latexes
  申请人：Stepan Company

  公开号：US20020040092A1

  公开（公告）日：2002-04-04

  Disclosed are antibacterial CASE materials comprising a latex comprising polymer particles and a surfactant component. Also disclosed are components and methods for forming such materials.

  所公开的抗菌 CASE 材料由包含聚合物颗粒和表面活性剂成分的胶乳组成。还公开了形成这种材料的成分和方法。
• Emulsion polymerization process utilizing ethylenically unsaturated amine salts of sulfonic, phosphoric and carboxylic acids
  申请人：STEPAN COMPANY, A corporation of the State of Delaware

  公开号：US20020161108A1

  公开（公告）日：2002-10-31

  Disclosed is an improved method of making polymers. The method utilizes at least one ethylenically unsaturated monomer and at least one polymerizable surface active agent. The polymerizable surface active agent is capable of co-polymerization with traditional monomers and/or polymerization with itself (i.e. homopolymerization) and is preferably substantially completely consumed during the course of the polymerization. Polymers produced by the method of the present invention are well suited for use in coatings, adhesives, sealants, elastomers and the like, as they form stable films, possess excellent adhesion properties and have improved hydrolytic stability characteristics. The present invention also encompasses homopolymeric surface active agents and their use in polymerization reactions.

  本发明公开了一种改进的聚合物制造方法。该方法利用至少一种乙烯基不饱和单体和至少一种可聚合表面活性剂。可聚合表面活性剂能与传统单体共聚合和/或与自身聚合（即均聚），最好在聚合过程中完全消耗。用本发明的方法生产的聚合物非常适合用于涂料、粘合剂、密封剂、弹性体等，因为它们能形成稳定的薄膜，具有优异的粘合性能和更好的水解稳定性。本发明还包括均聚物表面活性剂及其在聚合反应中的应用。
• Antimicrobial polymer latexes derived from unsaturated quaternary ammonium compounds and antimicrobial coatings, sealants, adhesives and elastomers produced from such latexes
  申请人：Stepan Company

  公开号：US20040092632A1

  公开（公告）日：2004-05-13

  An improved method of making CASE materials is provided, wherein the method utilizes a polymer latex derived from at least one ethylenically unsaturated monomer and at least one polymerizable surface active agent. The polymerizable surface active agent is capable of co-polymerization with traditional monomers and is preferably substantially completely consumed during the course of the polymerization. Latex polymers produced by the method of the present invention are well suited for use in coatings, adhesives, sealants, elastomers. Additionally, the present invention relates to improved coating, adhesive, sealant and elastomer (CASE) materials utilizing polymer latexes derived from various monomers and ethylenically unsaturated amine salts of sulfonic, phosphoric and/or carboxylic acids.

  本发明提供了一种制造 CASE 材料的改进方法，其中该方法利用了一种由至少一种乙烯基不饱和单体和至少一种可聚合表面活性剂制成的聚合物胶乳。可聚合表面活性剂能与传统单体共聚合，最好在聚合过程中完全消耗。用本发明的方法生产的乳胶聚合物非常适合用于涂料、粘合剂、密封剂和弹性体。此外，本发明还涉及利用由各种单体和磺酸、磷酸和/或羧酸的乙烯不饱和胺盐衍生的聚合物胶乳改进的涂料、粘合剂、密封剂和弹性体（CASE）材料。