p-Tolylsulfensaeure-trifluormethansulfonsaeure-anhydrid | 84224-62-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: p-Tolylsulfensaeure-trifluormethansulfonsaeure-anhydrid
• 英文别名: p-toluenesulfenyl trifluoromethane-sulfonate；p-Toluenesulfenyl triflate；(4-methylphenyl)sulfanyl trifluoromethanesulfonate
• CAS: 84224-62-4
• 化学式: C₈H₇F₃O₃S₂
• 分子量: 272.269
• InChiKey: IQRNVJITHHRLDX-UHFFFAOYSA-N

物化性质

• 沸点：
  287.3±50.0 °C(Predicted)
• 密度：
  1.52±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  77
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  4-甲基苯硫氯 、 silver trifluoromethanesulfonate 反应 1.0h， 生成 p-Tolylsulfensaeure-trifluormethansulfonsaeure-anhydrid
  参考文献：
  名称：

  Effenberger, Franz; Russ, Werner, Chemische Berichte, 1982, vol. 115, # 12, p. 3719 - 3736

  摘要：

  DOI：
• 作为试剂：
  描述：

  p-tolyl 2-O-benzoyl-3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside 、 methyl 2-O-benzoyl-3,4-di-O-benzyl-α-D-glucopyranoside 在 p-Tolylsulfensaeure-trifluormethansulfonsaeure-anhydrid 作用下， 反应 3.0h， 以91%的产率得到(2R,4aR,6R,7R,8S,8aR)-6-(((2R,3R,4S,5R,6S)-5-(benzoyloxy)-3,4-bis(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methoxy)-8-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl benzoate
  参考文献：
  名称：

  METHOD FOR PREPARING HEXOSE DERIVATIVES

  摘要：

  制备己糖衍生物的方法包括以下步骤：提供硅烷基化的己糖，将硅烷基化的己糖与第一羰基化合物在催化剂存在下处理，形成缩酮化的己糖，将缩酮化的己糖与第二羰基化合物处理后，再用第一还原剂处理，形成醚化的己糖，并将醚化的己糖转化为目标己糖衍生物，可以是2-醇己糖、3-醇己糖、4-醇己糖或6-醇己糖。具体来说，本发明可以采用高度选择性的方案制备己糖衍生物，以保护单糖单元的各个羟基，并以一锅法安装正交保护基图案。

  公开号：

  US20090105466A1

文献信息

• EFFENBERGER, F.;RUSS, W., CHEM. BER., 1982, 115, N 12, 3719-3736
  作者：EFFENBERGER, F.、RUSS, W.

  DOI：——

  日期：——
• Iterative one-pot oligosaccharide synthesis
  申请人：Huang Xuefei

  公开号：US20050136485A1

  公开（公告）日：2005-06-23

  A process for synthesizing an oligosaccharide includes (a) activating a protected glycosyl donor with a promoter in the absence of a glycosyl acceptor to produce a reactive intermediate, the glycosyl donor having an activatable aglycon at the anomeric carbon; (b) adding a protected glycosyl donor/acceptor to the reactive intermediate to produce a new glycosyl donor, the glycosyl donor/acceptor having both an activatable aglycon at the anomeric carbon and a free hydroxyl group; (c) repeating steps (a) and (b) to add any additional protected glycosyl donor/acceptors; and (d) adding a protected glycosyl acceptor to produce the oligosaccharide, the glycosyl acceptor having a free hydroxyl group and a non-activatable aglycon at the anomeric carbon.
• COMPOUND CONTAINING MODIFIED PHENOLIC HYDROXY GROUP, METHOD FOR PRODUCING COMPOUND CONTAINING MODIFIED PHENOLIC HYDROXY GROUP, PHOTOSENSITIVE COMPOSITION, RESIST MATERIAL, AND RESIST COATING FILM
  申请人：DIC Corporation

  公开号：US20170066703A1

  公开（公告）日：2017-03-09

  The present invention provides a compound containing a modified phenolic hydroxy group, which has a molecular structure represented by General Formula (1) except for a molecular structure represented by the following General Formula (2). In the formulas, R 1 represents a tertiary alkyl group, an alkoxyalkyl group, an aryloxyalkyl group, an acyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, a cyclic aliphatic hydrocarbon group containing a hetero atom, or a trialkylsilyl group; R 2 represents a hydrogen atom, an alkyl group, an alkoxy group, an aryl group which may have a substituent, an aralkyl group which may have a substituent, or a halogen atom; and R 3 represents an alkyl group which may have a substituent or an aryl group which may have a substituent.
• NOVEL SYNTHETIC ANTICANCER, ANTIFUNGAL, AND ANTIBACTERIAL VACCINES
  申请人：Wayne State University

  公开号：US20170348414A1

  公开（公告）日：2017-12-07

  Described herein are compounds for use in vaccine compositions which contain natural or synthetic carbohydrate antigens. Such vaccines may be highly immunologically active due to the conjugation with an immune-stimulating protein or with a monophosphorylated lipid A derivative, and may be self-adjuvanting due to the presence of a monophosphorylated lipid A derivative. Treatments for cancer and fungal and bacterial infections are described herein.
• US5380923A
  申请人：——

  公开号：US5380923A

  公开（公告）日：1995-01-10