2-allyloxyphenyllithium | 109900-88-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-allyloxyphenyllithium
• 英文别名: o-allyloxyphenyllithium
• CAS: 109900-88-1
• 化学式: C₉H₉LiO
• 分子量: 140.111
• InChiKey: FZZLHDKBHAOJBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.67
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-allyloxyphenyllithium 在 oxonium 、 lithium bromide 作用下， 生成 2-烯丙基酚
  参考文献：
  名称：

  Regio- and stereoselective copper-induced isomerization of 2-alkenyl 2-lithiophenyl ethers to 2-(2-alkenyl)phenols

  摘要：

  N-Allyl-N-(2-lithioallyl)aniline undergoes intramolecular carbometallation via 5-exo addition on treatment with CuCN. 2-Alkenyl 2-bromophenyl ethers rearrange to 2-(2-alkenyl)phenols by bromine-lithium exchange and further transmetallation with CuCN. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01379-8
• 作为产物：
  描述：

  1-溴-2-(2-丙烯-1-基氧基)-苯 在 叔丁基锂 作用下， 生成 2-allyloxyphenyllithium
  参考文献：
  名称：

  Regio- and stereoselective copper-induced isomerization of 2-alkenyl 2-lithiophenyl ethers to 2-(2-alkenyl)phenols

  摘要：

  N-Allyl-N-(2-lithioallyl)aniline undergoes intramolecular carbometallation via 5-exo addition on treatment with CuCN. 2-Alkenyl 2-bromophenyl ethers rearrange to 2-(2-alkenyl)phenols by bromine-lithium exchange and further transmetallation with CuCN. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01379-8

文献信息

• Nucleophilic substitution reactions of 1-sulfonyl substituted cyclopropenes with alkyl lithium reagents
  作者：Albert Padwa、M.Woods Wannamaker

  DOI：10.1016/s0040-4039(00)85335-6

  日期：1986.1

  Sulfonyl substituted cyclopropenes react with a variety of alkyl lithium reagents to give disubstituted cyclopropenes in good yield.

  磺酰基取代的环丙烯与多种烷基锂试剂反应，以高收率得到二取代的环丙烯。
• Base-pair recognition ability of hydroxyphenyl nucleobases in parallel triplex DNA
  作者：Yoshiyuki Hari、Satoshi Kashima、Hiroyasu Inohara、Shin Ijitsu、Takeshi Imanishi、Satoshi Obika

  DOI：10.1016/j.tet.2013.05.107

  日期：2013.8

  Oligonucleotides containing 2'-deoxyribonucleotides bearing hydroxyphenyl nucleobases or their 2',4'-BNA-modified analogs were synthesized, and the triplex-forming ability of their oligonucleotides with double-stranded DNA targets was evaluated by UV melting experiments. Results showed that 2'-deoxyribonucleotide bearing 2'-hydroxyphenyl nucleobase could be recognized by a dUA base pair while no affinity to a TA base pair was observed. The,4'-BNA modification led to a further increase in the binding affinity to a dUA base pair. The,4'-BNA bearing 3-hydroxyphenyl nucleobase showed moderate binding affinity to a TA base pair, but without selectivity. (C) 2013 Elsevier Ltd. All rights reserved.
• PADWA, ALBERT;KRUMPE, KEITH E.;TERRY, LENNY W.;WANNAMAKER, M. WOODS, J. ORG. CHEM., 54,(1989) N, C. 1635-1642
  作者：PADWA, ALBERT、KRUMPE, KEITH E.、TERRY, LENNY W.、WANNAMAKER, M. WOODS

  DOI：——

  日期：——
• PADWA A.; WANNAMAKER M. W., TETRAHEDRON LETT., 27,(1986) N 48, 5817-5820
  作者：PADWA A.、 WANNAMAKER M. W.

  DOI：——

  日期：——
• Regio- and stereoselective copper-induced isomerization of 2-alkenyl 2-lithiophenyl ethers to 2-(2-alkenyl)phenols
  作者：José Barluenga、Roberto Sanz、Francisco J. Fañanás

  DOI：10.1016/s0040-4039(97)01379-8

  日期：1997.8

  N-Allyl-N-(2-lithioallyl)aniline undergoes intramolecular carbometallation via 5-exo addition on treatment with CuCN. 2-Alkenyl 2-bromophenyl ethers rearrange to 2-(2-alkenyl)phenols by bromine-lithium exchange and further transmetallation with CuCN. (C) 1997 Elsevier Science Ltd.