1,4-bis-(2-methacryloyloxy-ethoxy)-benzene | 35057-36-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,4-bis-(2-methacryloyloxy-ethoxy)-benzene
• 英文别名: Bis-O-(2-methacryloyloxy-aethyl)-hydrochinon；1,4-Bis-(2-methacryloyloxy-aethoxy)-benzol；2,2'-(p-phenylenedioxy)-diethyl dimethacrylate；2-[4-[2-(2-Methylprop-2-enoyloxy)ethoxy]phenoxy]ethyl 2-methylprop-2-enoate
• CAS: 35057-36-4
• 化学式: C₁₈H₂₂O₆
• 分子量: 334.369
• InChiKey: MNJGAOVIZFAAHG-UHFFFAOYSA-N

物化性质

• 熔点：
  78 °C
• 沸点：
  458.3±35.0 °C(Predicted)
• 密度：
  1.117±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  甲基丙烯酸 、 对苯二酚二羟乙基醚 在 硫酸 、 对苯二酚 、 苯 作用下， 生成 1,4-bis-(2-methacryloyloxy-ethoxy)-benzene
  参考文献：
  名称：

  Esters of p-di(omega-hydroxyalkoxy)benzenes

  摘要：

  公开号：

  US02456318A1

文献信息

• [EN] DENTAL COMPOSITION AND USE THEREOF<br/>[FR] COMPOSITION DENTAIRE ET SON UTILISATION
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2015126862A1

  公开（公告）日：2015-08-27

  The invention relates to a dental composition comprising polymerizable monomer (1), initiator component(s), filler component(s) in an amount of more than about 20 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, and oxygen, bisphenol moieties. The invention also relates to the use of the dental composition as or for producing a dental filling material, crown and bridge material, inlay, onlay, veneer or dental mill blank.

  该发明涉及一种牙科组合物，包括可聚合单体（1），引发剂成分，填料成分，其含量超过整个组合物重量的20重量％，可聚合单体（1）的特征如下：具有正好两个（甲基）丙烯酸酯反应基团，具有非对称的骨架作为（甲基）丙烯酸酯反应基团之间的连接，两个（甲基）丙烯酸酯反应基团附着在非对称单体骨架上作为烷基酯，非对称骨架包括酚型芳香基团，可聚合单体（1）不含有酸性基团，除碳、氢和氧之外的其他原子，双酚基团。该发明还涉及将该牙科组合物用作或用于生产牙科充填材料，牙冠和桥梁材料，嵌体，瓷贴面或牙科铣削坯料。
• [EN] ADHESIVE BONDING COMPOSITION AND USE THEREOF<br/>[FR] COMPOSITION DE LIAISON ADHÉSIVE ET SON UTILISATION
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2015126865A1

  公开（公告）日：2015-08-27

  An adhesive dental composition comprising apolymerizable monomer (1), a polymerizable monomer (2) comprising an acidic moiety,initiator component(s), filler component(s) in an amount of less than about 15 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, and oxygen, bisphenol moieties. The invention also relates to the use of the adhesive dental composition as dental adhesive, sealant, cement or for bonding or cementing a material to the surface of hard dental tissue.

  一种粘合剂牙科组合物，包括可聚合单体（1）、含有酸性基团的可聚合单体（2）、引发剂组分、填料组分，其含量不超过整个组合物重量的约15重量％，其中可聚合单体（1）具有以下特征：具有正好两个（甲基）丙烯酸酯反应基团，具有不对称的骨架作为连接（甲基）丙烯酸酯反应基团的链，两个（甲基）丙烯酸酯反应基团附着在不对称单体骨架上作为烷基酯，不对称骨架包括酚类的一个芳香基团，可聚合单体（1）不含有酸性基团、除碳、氢和氧之外的其他原子、双酚基团。该发明还涉及将该粘合剂牙科组合物用作牙科粘合剂、密封剂、水泥或用于将材料粘合或水泥到硬质牙齿表面的用途。
• 1,3,5-Triazines for Treatment of Viral Diseases
  申请人：Daifuku Richard

  公开号：US20070207973A1

  公开（公告）日：2007-09-06

  The present invention provides compounds and methods for treatment of viral diseases and cancer.

  本发明提供了用于治疗病毒性疾病和癌症的化合物和方法。
• 1,3,5-Triazines for treatment of viral diseases
  申请人：Koronis Pharmaceuticals, Inc.

  公开号：US20040127436A1

  公开（公告）日：2004-07-01

  The present invention provides compounds and methods for treatment of viral diseases and cancer.

  本发明提供了用于治疗病毒性疾病和癌症的化合物和方法。
• Novel methods of imaging and treatment with targeted compositions
  申请人：——

  公开号：US20030157025A1

  公开（公告）日：2003-08-21

  Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The scanning may comprise exposing the patient to a first type of ultrasound energy and then interrogating the patient using a second type of ultrasound energy. The targeting ligand preferably targets tissues, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The methods may be used to detect a thrombus, enhancement of an old or echogenic thrombus, low concentrations of vesicles and vesicles targeted to tissues, cells or receptors.

  新型超声波方法包括向患者施加含有脂质、蛋白质或聚合物的气囊组成的有针对性的气囊组合物，该气囊包含一种气体，并与一个靶向配体结合，然后使用超声波扫描患者。扫描可能包括将患者暴露于第一种超声波能量，然后使用第二种超声波能量对患者进行询问。靶向配体首选靶向组织、细胞或受体，包括心肌细胞、内皮细胞、上皮细胞、肿瘤细胞和糖蛋白GPIIbIIIa受体。该方法可用于检测血栓、旧血栓或回声增强、低浓度气囊和靶向组织、细胞或受体的气囊。