3-allyl-1-benzyl-2,2-dimethylaziridine | 831200-96-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-allyl-1-benzyl-2,2-dimethylaziridine
• 英文别名: Aziridine, 2,2-dimethyl-1-(phenylmethyl)-3-(2-propenyl)-；1-benzyl-2,2-dimethyl-3-prop-2-enylaziridine
• CAS: 831200-96-5
• 化学式: C₁₄H₁₉N
• 分子量: 201.312
• InChiKey: PAOFBXAMLWDPQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  苄胺 、 alkaline earth salt of/the/ methylsulfuric acid 以 四氢呋喃 、 甲苯 为溶剂， 反应 14.0h， 生成 3-allyl-1-benzyl-2,2-dimethylaziridine
  参考文献：
  名称：

  α-Phenylselanyl imines: preparation of β-phenylselanyl amines and original synthesis of allylaziridines

  摘要：

  Resorting to suitable methods, a wide variety of alpha-phenylselanyl imines 2-5 were prepared from alpha-phenylselanyl aldehydes and alpha-phenylselanyl ketones 1. These compounds were reduced to afford beta-phenylselanyl amines 6-9. Our experimental conditions have limited the well known deselenenylation side-reaction occurring with most hydrides. On the other hand, the reaction of alpha-phenylselanyl imines 2 with organometallics led to the expected addition products only in the case of allylated derivatives. Depending on the temperature, either alpha-phenylselanyl amines 11 or unexpected allylaziridines 12 were recovered. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.10.065

文献信息

• α-Phenylselanyl imines: preparation of β-phenylselanyl amines and original synthesis of allylaziridines
  作者：Catherine Miniejew、Francis Outurquin、Xavier Pannecoucke

  DOI：10.1016/j.tet.2004.10.065

  日期：2005.1

  Resorting to suitable methods, a wide variety of alpha-phenylselanyl imines 2-5 were prepared from alpha-phenylselanyl aldehydes and alpha-phenylselanyl ketones 1. These compounds were reduced to afford beta-phenylselanyl amines 6-9. Our experimental conditions have limited the well known deselenenylation side-reaction occurring with most hydrides. On the other hand, the reaction of alpha-phenylselanyl imines 2 with organometallics led to the expected addition products only in the case of allylated derivatives. Depending on the temperature, either alpha-phenylselanyl amines 11 or unexpected allylaziridines 12 were recovered. (C) 2004 Elsevier Ltd. All rights reserved.