3-(2-溴棕榈酰氧基)-4-三甲基铵丁酸盐 | 32886-14-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-(2-溴棕榈酰氧基)-4-三甲基铵丁酸盐
• 英文名称: 2-Bromopalmitoylcarnitine
• 英文别名: 3-(2-bromohexadecanoyloxy)-4-(trimethylazaniumyl)butanoate
• CAS: 32886-14-9
• 化学式: C23H44BrNO4
• 分子量: 478.5
• InChiKey: LYHAKRWRNXBZLK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  29
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  66.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Reduction of hair growth
  申请人：——

  公开号：US20030153619A1

  公开（公告）日：2003-08-14

  Mammalian hair growth can be reduced by topical application of an inhibitor of fatty acid metabolism.

  局部使用脂肪酸代谢抑制剂可减少哺乳动物毛发的生长。
• REDUCTION OF HAIR GROWTH
  申请人：THE GILLETTE COMPANY

  公开号：EP1469816A2

  公开（公告）日：2004-10-27
• USE OF CPT-1 MODULATORS AND COMPOSITIONS THEREOF
  申请人：Avon Products, Inc.

  公开号：EP2819752A1

  公开（公告）日：2015-01-07
• Use of CPT-1 Modulators and Compositions Thereof
  申请人：Avon Products, Inc.

  公开号：US20130224318A1

  公开（公告）日：2013-08-29

  The present invention describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Carnitine Palmitoyl Transferase-1 (CPT-1) modulators, optionally with other anti-lipid agents; and also describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis.
• METHODS FOR REDUCING PROTEOTOXICITY
  申请人：The Regents of the University of California

  公开号：US20180216113A1

  公开（公告）日：2018-08-02

  The present disclosure provides methods of reducing protein misfolding and/or aggregation in a cell. The present disclosure provides methods of treating diseases and disorders associated with protein misfolding and/or aggregation.