bis-N,N'-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)pyromellitic diimide | 261374-61-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: bis-N,N'-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)pyromellitic diimide
• 英文别名: 2,6-Bis[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]pyrrolo[3,4-f]isoindole-1,3,5,7-tetrone；2,6-bis[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]pyrrolo[3,4-f]isoindole-1,3,5,7-tetrone
• CAS: 261374-61-2
• 化学式: C₂₆H₃₆N₂O₁₂
• 分子量: 568.578
• InChiKey: VLNRGWXGFUDNHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  40
• 可旋转键数：
  22
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  171
• 氢给体数：
  2
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  1,4,5,8-萘四甲酰基二酰亚胺 、 bis-N,N'-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)pyromellitic diimide 在 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  Macrocyclization and Molecular Interlocking via Mitsunobu Alkylation:  Highlighting the Role of C−H···O Interactions in Templating

  摘要：

  [GRAPHICS]A series of diimide-based macrocycles have been prepared using Mitsunobu mediated alkylation as the macrocyclization step. These macrocycles could not be incorporated into [2]catenanes using previously established building blocks and coupling methodology. However, when one of the macrocycle syntheses was conducted in the presence of a dinaphtho crown ether, catenane formation was achieved. This result is discussed in terms of the ability of the components to establish intermolecular C-H ... O hydrogen-bonding contacts.

  DOI：

  10.1021/ol991289w
• 作为产物：
  描述：

  均苯四甲酸二酐 、 1-氨基-3,6,9-三噁-11-十一醇 以 N,N-二甲基甲酰胺 为溶剂， 反应 16.0h， 以28%的产率得到bis-N,N'-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)pyromellitic diimide
  参考文献：
  名称：

  Macrocyclization and Molecular Interlocking via Mitsunobu Alkylation:  Highlighting the Role of C−H···O Interactions in Templating

  摘要：

  [GRAPHICS]A series of diimide-based macrocycles have been prepared using Mitsunobu mediated alkylation as the macrocyclization step. These macrocycles could not be incorporated into [2]catenanes using previously established building blocks and coupling methodology. However, when one of the macrocycle syntheses was conducted in the presence of a dinaphtho crown ether, catenane formation was achieved. This result is discussed in terms of the ability of the components to establish intermolecular C-H ... O hydrogen-bonding contacts.

  DOI：

  10.1021/ol991289w