1,4-Phenylen-bis-oxyacetaldehyd | 24535-81-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,4-Phenylen-bis-oxyacetaldehyd
• 英文别名: 2-[4-(2-Oxoethoxy)phenoxy]acetaldehyde
• CAS: 24535-81-7
• 化学式: C₁₀H₁₀O₄
• 分子量: 194.187
• InChiKey: FMGNNEMPSLSNPH-UHFFFAOYSA-N

物化性质

• 熔点：
  90-91 °C
• 沸点：
  344.5±22.0 °C(Predicted)
• 密度：
  1.176±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4-Phenylen-bis-oxyacetaldehyd 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 以3.87 g的产率得到对苯二酚二羟乙基醚
  参考文献：
  名称：

  新核的合成及其在聚酯树枝状聚合物制备中的应用

  摘要：

  已经通过还原还原性臭氧分解产物以一致的一锅方式从末端的烯丙基制备了六种由羟基基团封端的树枝状聚合物和树枝状核心，所述羟基不能被酚解或不能被氢解。一些末端烯丙基衍生物是新的，而另一些已通过新方法制备。2，2′-双（羟甲基）丙酸的众所周知的O-亚苄基衍生物被证明是顺式-立体异构体。已经制备了新的AB 3型酸酐，三（苄氧基甲基）乙酸酐。结果表明，这些核和树枝状分子可以组装成第一代和第二代均聚物和混合聚酯树枝状聚合物。

  DOI：

  10.1016/j.tet.2010.10.018
• 作为产物：
  描述：

  1,4-二(丙-2-烯氧基)苯 在 臭氧 、 二甲基硫 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 生成 1,4-Phenylen-bis-oxyacetaldehyd
  参考文献：
  名称：

  新核的合成及其在聚酯树枝状聚合物制备中的应用

  摘要：

  已经通过还原还原性臭氧分解产物以一致的一锅方式从末端的烯丙基制备了六种由羟基基团封端的树枝状聚合物和树枝状核心，所述羟基不能被酚解或不能被氢解。一些末端烯丙基衍生物是新的，而另一些已通过新方法制备。2，2′-双（羟甲基）丙酸的众所周知的O-亚苄基衍生物被证明是顺式-立体异构体。已经制备了新的AB 3型酸酐，三（苄氧基甲基）乙酸酐。结果表明，这些核和树枝状分子可以组装成第一代和第二代均聚物和混合聚酯树枝状聚合物。

  DOI：

  10.1016/j.tet.2010.10.018

文献信息

• POLYESTER ELASTOMERS, PROCESSES FOR PREPARING THE SAME, AND COMPOSITIONS OF THE SAME
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0893463A1

  公开（公告）日：1999-01-27

  First aspect of the invention provides a novel polyester elastomer having a high melting point, which comprises a crystalline aromatic polyester which is a hard component, at least one kind selected from an aliphatic polyester, a polyether, and a polycarbonate which are a soft component, and a compound containing isocyanate groups, and which can be obtained in a short preparation time of period. Second aspect of the invention provides a novel polyester elastomer having a high melting point, which is obtained by allowing to react an epoxy group-containing compound which contains at least one of an epoxy compound having at least two epoxy groups in the molecule in place of the compound containing isocyanate groups in the first aspect of the invention, and which can be obtained in a short preparation time of period. Third aspect of the invention provides a polyester elastomer having a hard segment which comprises a polyalkylene naphthalate and an aliphatic polyester having a specified average block chain length, and a process for the preparation thereof, and which is excellent in a heat resistance, oil resistance, abrasion resistance, impact resistance, and hydrolysis resistance, and which is preferably employed as parts for cars, large-sized machines, industrial machines, and home electric appliances. Fourth aspect of the invention provides a process for the preparation of a polyester elastomer which comprises an aromatic polyester resin, an aliphatic polyester resin which have a specified molecular weight, and a dibasic acid (C) or an anhydride thereof, and which is excellent in a heat resistance and rigidity. Fifth aspect of the invention provides a polyester elastomer composition which comprises mixing a polyester elastomer with a specified amount of an epoxy-modified polymer, and which is excellent in a heat resistance, oil resistance, abrasion resistance, impact resistance, and hydrolysis resistance. Sixth aspect of the invention provides a molded article which includes, for example, fibers, films, sheets, bottles, and sheet-molded articles, which comprises an aromatic polyester resin which is a hard segment primarily containing a polyethylene terephthalate or a polyethylene terenaphthalate and at least one kind of a resin which is a soft segment selected from the group consisting of an aliphatic polyester, polycarbonate, and polyether. Seventh aspect of the invention provides an aliphatic polyester elastomer which comprises an aliphatic polyester in which a hard segment and a soft segment which construct a polyester elastomer are different from each other, and which is excellent in a moldability, ductility, impact resistance, and hydrolysis resistance, and which has a low melting point.

  本发明的第一方面提供了一种具有高熔点的新型聚酯弹性体，它包括作为硬组分的结晶芳香族聚酯，作为软组分的至少一种选自脂肪族聚酯、聚醚和聚碳酸酯的物质，以及一种含有异氰酸酯基团的化合物，并且可以在较短的制备时间内获得。本发明的第二方面提供了一种具有高熔点的新型聚酯弹性体，它是通过使一种含环氧基团的化合物发生反应而获得的，该化合物含有至少一种在分子中具有至少两个环氧基团的环氧化合物，以代替本发明第一方面中含有异氰酸酯基团的化合物，并且可以在较短的制备时间内获得。本发明的第三方面提供了一种具有硬段的聚酯弹性体，它由聚萘二甲酸烷基酯和具有特定平均嵌段链长的脂肪族聚酯组成，并提供了制备该弹性体的工艺，该弹性体具有优异的耐热性、耐油性、耐磨性、耐冲击性和耐水解性，最好用作汽车、大型机械、工业机械和家用电器的部件。本发明的第四个方面提供了一种聚酯弹性体的制备方法，它由芳香族聚酯树脂、具有特定分子量的脂肪族聚酯树脂和二元酸（C）或其酸酐组成，具有优异的耐热性和刚性。本发明的第五个方面提供了一种聚酯弹性体组合物，它包括将聚酯弹性体与一定量的环氧改性聚合物混合，该组合物具有优异的耐热性、耐油性、耐磨性、耐冲击性和抗水解性。本发明的第六个方面提供了一种模塑制品，例如包括纤维、薄膜、片材、瓶子和片材模塑制品，它由芳香族聚酯树脂和至少一种树脂组成，前者是主要含有聚对苯二甲酸乙二醇酯或聚对苯二甲酸乙二醇酯的硬段，后者是从脂肪族聚酯、聚碳酸酯和聚醚组成的组中选出的软段。本发明的第七个方面提供了一种脂肪族聚酯弹性体，该弹性体由脂肪族聚酯组成，其中构成聚酯弹性体的硬段和软段彼此不同，该弹性体具有优异的成型性、延展性、抗冲击性和抗水解性，并且熔点较低。
• Polyester elastomers, processes for preparing the same, and compositions of the same
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1314749A2

  公开（公告）日：2003-05-28

  First aspect of the invention provides a novel polyester elastomer having a high melting point, which comprises a crystalline aromatic polyester which is a hard component, at least one kind selected from an aliphatic polyester, a polyether, and a polycarbonate which are a soft component, and a compound containing isocyanate groups, and which can be obtained in a short preparation time of period. Second aspect of the invention provides a novel polyester elastomer having a high melting point, which is obtained by allowing to react an epoxy group-containing compound which contains at least one of an epoxy compound having at least two epoxy groups in the molecule in place of the compound containing isocyanate groups in the first aspect of the invention, and which can be obtained in a short preparation time of period. Third aspect of the invention provides a polyester elastomer having a hard segment which comprises a polyalkylene naphthalate and an aliphatic polyester having a specified average block chain length, and a process for the preparation thereof, and which is excellent in a heat resistance, oil resistance, abrasion resistance, impact resistance, and hydrolysis resistance, and which is preferably employed as parts for cars, large-sized machines, industrial machines, and home electric appliances. Fourth aspect of the invention provides a process for the preparation of a polyester elastomer which comprises an aromatic polyester resin, an aliphatic polyester resin which have a specified molecular weight, and a dibasic acid (C) or an anhydride thereof, and which is excellent in a heat resistance and rigidity. Fifth aspect of the invention provides a polyester elastomer composition which comprises mixing a polyester elastomer with a specified amount of an epoxy-modified polymer, and which is excellent in a heat resistance, oil resistance, abrasion resistance, impact resistance, and hydrolysis resistance. Sixth aspect of the invention provides a molded article which includes, for example, fibers, films, sheets, bottles, and sheet-molded articles, which comprises an aromatic polyester resin which is a hard segment primarily containing a polyethylene terephthalate or a polyethylene terenaphthalate and at least one kind of a resin which is a soft segment selected from the group consisting of an aliphatic polyester, polycarbonate, and polyether. Seventh aspect of the invention provides an aliphatic polyester elastomer which comprises an aliphatic polyester in which a hard segment and a soft segment which construct a polyester elastomer are different from each other, and which is excellent in a moldability, ductility, impact resistance, and hydrolysis resistance, and which has a low melting point.

  本发明的第一方面提供了一种具有高熔点的新型聚酯弹性体，它包括作为硬组分的结晶芳香族聚酯，作为软组分的至少一种选自脂肪族聚酯、聚醚和聚碳酸酯的物质，以及一种含有异氰酸酯基团的化合物，并且可以在较短的制备时间内获得。本发明的第二方面提供了一种具有高熔点的新型聚酯弹性体，它是通过使一种含环氧基团的化合物发生反应而获得的，该化合物含有至少一种在分子中具有至少两个环氧基团的环氧化合物，以代替本发明第一方面中含有异氰酸酯基团的化合物，并且可以在较短的制备时间内获得。本发明的第三方面提供了一种具有硬段的聚酯弹性体，它由聚萘二甲酸烷基酯和具有特定平均嵌段链长的脂肪族聚酯组成，并提供了制备该弹性体的工艺，该弹性体具有优异的耐热性、耐油性、耐磨性、耐冲击性和耐水解性，最好用作汽车、大型机械、工业机械和家用电器的部件。本发明的第四个方面提供了一种聚酯弹性体的制备方法，它由芳香族聚酯树脂、具有特定分子量的脂肪族聚酯树脂和二元酸（C）或其酸酐组成，具有优异的耐热性和刚性。本发明的第五个方面提供了一种聚酯弹性体组合物，它包括将聚酯弹性体与一定量的环氧改性聚合物混合，该组合物具有优异的耐热性、耐油性、耐磨性、耐冲击性和抗水解性。本发明的第六个方面提供了一种模塑制品，例如包括纤维、薄膜、片材、瓶子和片材模塑制品，它由芳香族聚酯树脂和至少一种树脂组成，前者是主要含有聚对苯二甲酸乙二醇酯或聚对苯二甲酸乙二醇酯的硬段，后者是从脂肪族聚酯、聚碳酸酯和聚醚组成的组中选出的软段。本发明的第七个方面提供了一种脂肪族聚酯弹性体，该弹性体由脂肪族聚酯组成，其中构成聚酯弹性体的硬段和软段彼此不同，该弹性体具有优异的成型性、延展性、抗冲击性和抗水解性，并且熔点较低。
• Electrochemical pH Measurement
  申请人：SCHLUMBERGER TECHNOLOGY B.V.

  公开号：EP2660588A1

  公开（公告）日：2013-11-06

  A method of measuring pH of aqueous liquid with little or no buffer present uses an electrochemical sensor which comprises a plurality of electrodes with a redox active organic compound attached to an electrode and having at least one functional group convertible electrochemically between reduced and oxidized forms with transfer of at least one proton between the compound and surrounding aqueous phase, wherein the compound has at least one substituent group which promotes hydrogen bonding at a said functional group and thereby increases the reaction rate of proton transfer. The substituent group may form an internal hydrogen bond with a redox-convertible group or may enhance polarity to promote electrostatic interaction with water molecules and reduce activation energy. Typical examples include alizarin or 1,2-dihydroxy-anthraquinone (RN=72-48-0), quinizarin or 1,4-dihydroxy-anthraquinone (RN=81-64-1), 2-acetoxy-benzoquinone (RN=1125-55-9), chloranil or 2,3,4,5-tetrachloro-benzoquinone (RN=118-75-2) and 1,4-diamino-2,3-dichloro-anthraquinone (RN=81-42-5) deposited on a glassy carbon electrode. In this way, anomalous measurements at low ionic strength and low concentrations of pH buffering species can be overcome. Such an electrochemical sensor may be used for pH measurement in computer controlled equipment for processing an aqueous liquid.

  一种测量含水液体 pH 值的方法，使用了一种电化学传感器，该传感器包括多个电极，电极上附有氧化还原活性有机化合物，该化合物具有至少一个可在还原和氧化形式之间进行电化学转换的官能团，该化合物与周围水相之间可转移至少一个质子，其中该化合物具有至少一个取代基，可促进所述官能团上的氢键，从而提高质子转移的反应速率。取代基可以与可氧化还原的基团形成内部氢键，也可以增强极性，促进与水分子的静电作用，降低活化能。典型的例子包括茜素或 1,2-二羟基蒽醌（RN=72-48-0），喹吖啶或 1,4-二羟基蒽醌（RN=81-64-1），2-乙酰氧基苯醌（RN=1125-55-9）、氯苯或 2,3,4,5- 四氯苯醌（RN=118-75-2）和 1,4-二氨基-2,3-二氯蒽醌（RN=81-42-5）沉积在玻璃碳电极上。这样，就可以克服在低离子强度和低浓度 pH 缓冲物质条件下的异常测量。这种电化学传感器可用于处理水性液体的计算机控制设备的 pH 值测量。
• Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition
  申请人：Gupta K. Shyam

  公开号：US20060074108A1

  公开（公告）日：2006-04-06

  This invention relates to compounds that are selective inhibitors of Matrix Metalloprotease (also known as Matrix Metalloproteinase, MMP), to cosmetic and pharmaceutical compositions containing them, and to their use in the prevention and/or treatment of ailments associated with MMP, including inflammation, wound healing, skin aging, skin tone discoloration, body odor, oral cavity odor, rosacea, acne, and hair growth modulation.

  本发明涉及基质金属蛋白酶（又称基质金属蛋白酶，MMP）选择性抑制剂的化合物、含有这些化合物的化妆品和药物组合物，以及它们在预防和/或治疗与 MMP 有关的疾病中的用途，包括炎症、伤口愈合、皮肤老化、肤色变色、体味、口腔异味、酒渣鼻、痤疮和毛发生长调节。
• Synthesis of some phenoxyacetaldehydes and their derivatives
  作者：S. A. Zotova

  DOI：10.1007/bf00761340

  日期：1969.9