甲基丙烯酸甲酯、甲基丙烯酸-2-(二甲氨基)乙酯的聚合物 | 26222-42-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 甲基丙烯酸甲酯、甲基丙烯酸-2-(二甲氨基)乙酯的聚合物
• 英文名称: 2-(Dimethylamino)ethyl 2-methylprop-2-enoate;methyl 2-methylprop-2-enoate
• CAS: 26222-42-4
• 化学式: C13H23NO4
• 分子量: 257.33
• InChiKey: LIMHZMBWISMZJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE)
  申请人：TOSOH ORGANIC CHEMICAL CO., LTD.

  公开号：US20150246876A1

  公开（公告）日：2015-09-03

  Provided are high purity sodium p-styrenesulfonate with an excellent hue which is useful as a reactive emulsifier or dispersant for producing a polymer emulsion, or synthetic starch for clothing ironing and poly(sodium p-styrene-sulfonate) with an excellent hue using the same or sodium p-styrenesulfonate improved in fluidity while keeping good solubility. An aqueous p-β-bromoethylbenzenesulfonic acid solution and an aqueous sodium hydroxide solution are reacted under specific conditions to control the particle size, thereby obtaining sodium p-styrenesulfonate particles improved in a balance between fluidity and solubility, and further, impurities such as isomers are reduced, thereby obtaining high-purity sodium p-styrenesulfonate with an excellent hue.

  提供高纯度的对苯乙烯磺酸钠，具有优异的色泽，可用作反应性乳化剂或分散剂，用于生产聚合物乳液或合成淀粉用于衣物熨烫以及使用相同或改善流动性但保持良好溶解性的对苯乙烯磺酸钠制备优良色泽的聚(对苯乙烯磺酸钠)。在特定条件下，将水溶性的对β-溴乙基苯磺酸和氢氧化钠水溶液反应，以控制粒子大小，从而获得改善流动性和溶解性平衡的对苯乙烯磺酸钠颗粒，进一步减少异构体等杂质，从而获得具有优异色泽的高纯度对苯乙烯磺酸钠。
• Improved blood-purifying membrane and process for preparation thereof
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0232442A1

  公开（公告）日：1987-08-19

  Disclosed is a blood-purifying regenerated cellulose membrane composed of regenerated cellulose, a blood-con­tacting surface of said membrane being coated with a polymeric substance. The polymeric substance is a homopolymer or copolymer of a basic vinyl monomer having an amino group in the side chain. The membrane is characterized in that the occurrence of the leukopenia phenomenon and the activation of the complement system are mitigated and such improved properties can last for a long period.

  本发明公开了一种血液净化再生纤维素膜，该膜由再生纤维素组成，其与血液接触的表面涂有聚合物质。聚合物质是侧链中含有氨基的基本乙烯基单体的均聚物或共聚物。这种膜的特点是可减轻白细胞减少现象的发生和补体系统的激活，而且这种改进的特性可持续很长时间。
• CARBON DIOXIDE COMPOSITIONS FOR EXTERNAL USE AND PROCESS FOR PRODUCING THE SAME
  申请人：Neochemir Inc.

  公开号：EP1470820A1

  公开（公告）日：2004-10-27

  Carbon dioxide is dissolved in a non-bubble state in a viscous material comprising at least water and a thickener. A production method of this carbon dioxide composition for external use comprises the steps of introducing at least water and a thickener as raw materials into a carbon dioxide-impermeable sealable container, reducing the pressure inside the container to degas the raw materials, and filling carbon dioxide into the container and maintaining a sealed state, and the step of mixing the raw materials to prepare a viscous material, wherein at least during the step of filling carbon dioxide into the container. Another carbon dioxide composition for external use comprises at least a fermentation microbe, a metabolite of the fermentation microbe, a thickener, water, and carbon dioxide. With these carbon dioxide compositions for external use, strong cosmetic and medical effects are readily obtained with a small amount of the composition.

  二氧化碳以非气泡状态溶解在至少由水和增稠剂组成的粘性材料中。这种外用二氧化碳组合物的生产方法包括以下步骤：将至少水和增稠剂作为原料引入可渗透二氧化碳的密封容器，降低容器内的压力使原料脱气，将二氧化碳注入容器并保持密封状态，以及将原料混合以制备粘稠材料，其中至少在将二氧化碳注入容器的步骤中。另一种外用二氧化碳组合物至少包括发酵微生物、发酵微生物的代谢物、增稠剂、水和二氧化碳。使用这些二氧化碳外用组合物，只需少量的组合物就可以获得很强的美容和医疗效果。
• EXTENDED RELEASE FORMULATION
  申请人：Shionogi & Co., Ltd.

  公开号：EP3088002A1

  公开（公告）日：2016-11-02

  The present invention is a sustained release formulation which is capable of cotrolling dissolution of a drug and of enduring peristaltic movement of the gastrointestinal tract. Specifically, the present invention is: a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and an alkali agent, wherein the alkali metal salt is a sodium salt or a potassium salt, and the alkali agent is a magnesium oxide; or a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and a water soluble polymer or a hydrophobic base, wherein the alkali metal salt is a sodium salt or a potassium salt. The present invention is thus capable of providing an extended release formulation that controls dissolution of a drug and endures peristaltic movement of the gastrointestinal tract.

  本发明是一种缓释制剂，能够使药物同步溶解并经受住胃肠道的蠕动。具体来说，本发明是一种固体制剂，包括药物、可瑞卡麦卢糖钠、碱金属盐或碱氧化物和碱剂，其中碱金属盐是钠盐或钾盐，碱剂是氧化镁；或一种固体制剂，包括药物、可瑞卡麦卢糖钠、碱金属盐或碱氧化物和水溶性聚合物或疏水基，其中碱金属盐是钠盐或钾盐。因此，本发明能够提供一种缓释制剂，这种制剂能够控制药物的溶解，并能承受胃肠道的蠕动。
• Combination of polyvinyl acetate with water-insoluble, acid-insoluble, or alkali-insoluble polymers used for the production of film coatings with highly controlled release and high stability
  申请人：Kolter Karl

  公开号：US20050106252A1

  公开（公告）日：2005-05-19

  The invention relates to the combination of polyvinyl acetate and water-insoluble, acid-insoluble, or alkali-insoluble polymers used for producing film coatings for forms of administration in which agents are released in a controlled manner, and methods for the production thereof. The controlled-release properties can be specifically adjusted by means of said combinations, resulting in films having excellent mechanical stability and storage stability. In particular, agents are released independent of the pH by means of the inventive forms of administration.

  本发明涉及聚醋酸乙烯酯与水不溶性、酸不溶性或碱不溶性聚合物的组合，用于生产以可控方式释放药剂的给药形式的薄膜涂层，以及其生产方法。通过上述组合，可对控释特性进行专门调整，从而使薄膜具有出色的机械稳定性和储存稳定性。特别是，通过本发明的给药形式，药剂的释放不受 pH 值的影响。