甲基丙烯酸酯含氢聚硅氧烷 | 9004-73-3

• 物质功能分类: 医药中间体 - 原料药中间体
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环化合物
• 中文名称: 甲基丙烯酸酯含氢聚硅氧烷
• 中文别名: 202含氢硅油；聚甲基聚硅氧烷；聚（甲基氢硅氧烷）
• 英文名称: Methicone
• CAS: 9004-73-3
• 化学式: C5H11OSi
• 分子量: 115.23
• InChiKey: TXYXVOOPRILIHR-UHFFFAOYSA-N

物化性质

• 沸点：
  >177 °C(lit.)
• 密度：
  1.006 g/mL at 25 °C(lit.)
• 闪点：
  250 °F
• 溶解度：
  most ethereal, chlorinated, or hydrocarbon solvents as well as EtOH, i-PrOH, warm DMF, and warm NMP; insoluble in MeOH, DMSO, acetonitrile, and water.
• 稳定性/保质期：

  在常温常压下保持稳定，请避免光照、明火及高温环境。

计算性质

• 辛醇/水分配系数(LogP)：
  1.42
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 安全说明：
  S24/25
• 危险品标志：
  Xi
• 危险类别码：
  R10

SDS

Name:	Polymethylhydrosiloxane ca.99.5% silicon Material Safety Data Sheet
Synonym:	Methylpolysilicone; Methylpolysiloxane; Poly[oxy(methylsilylene)]; Polyalkylhydrosiloxan
CAS:	9004-73-3

Section 1 - Chemical Product MSDS Name:Polymethylhydrosiloxane ca.99.5% silicon Material Safety Data Sheet
Synonym:Methylpolysilicone; Methylpolysiloxane; Poly[oxy(methylsilylene)]; Polyalkylhydrosiloxan

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
9004-73-3	Polymethylhydrosiloxane	95	unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
This material is lighter than water and insoluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 9004-73-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Clear liquid
Color: clear, colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: 10-27 sq. 25.00
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: 121 deg C ( 249.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >300 deg C
Solubility in water: practically insoluble
Specific Gravity/Density: .9950g/cm3
Molecular Formula: C3H9SiOCH3HOSixSiC3H9
Molecular Weight: 222.4093

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Strong acids, strong bases, strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, silicon dioxide.
Hazardous Polymerization: Has not been reported.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 9004-73-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Polymethylhydrosiloxane - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 9004-73-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 9004-73-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 9004-73-3 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

简介

聚甲基聚硅氧烷是一种有机硅聚合物，主要用于制备电子插接件等材料。此外，根据文献报道，它还可以用于制备中空玻璃用阻燃型硅酮密封胶和热防护有机涂层。

制备

将20克正硅酸乙酯、15克水和85克乙醇混合均匀，加入1克质量浓度为37%的盐酸，在80℃下反应30分钟。随后，加入100克甲基苯基二甲氧基硅烷，在80℃下继续反应120分钟。再加入5克二乙烯基四甲基二硅氧烷，在80℃下再次反应120分钟后，减压除去溶剂，并用乙酸乙酯萃取三次，最终得到聚甲基聚硅氧烷。