compound | 494764-40-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: compound
• 英文别名: (E,E)-N,N'-(Ethane-1,2-diyl)bis(1-{2-[(prop-2-en-1-yl)oxy]phenyl}methanimine)；1-(2-prop-2-enoxyphenyl)-N-[2-[(2-prop-2-enoxyphenyl)methylideneamino]ethyl]methanimine
• CAS: 494764-40-8
• 化学式: C₂₂H₂₄N₂O₂
• 分子量: 348.445
• InChiKey: MZDHAGBXYCWHTO-UHFFFAOYSA-N

物化性质

• 沸点：
  511.6±50.0 °C(Predicted)
• 密度：
  0.99±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  43.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  compound 、 2-(萘-1-基氧基)乙酰氯 以 二氯甲烷 为溶剂， 反应 0.5h， 以46%的产率得到(3R,4S)-3-naphthalen-1-yloxy-1-[2-[(3R,4S)-3-naphthalen-1-yloxy-2-oxo-4-(2-prop-2-enoxyphenyl)azetidin-1-yl]ethyl]-4-(2-prop-2-enoxyphenyl)azetidin-2-one
  参考文献：
  名称：

  Staudinger Ketene−Imine Cycloaddition, RCM Approach to Macrocrocyclic Bisazetidinones

  摘要：

  Application of Staudinger ketene-imine cycloaddition reaction to bis-o-allyloxyarylideneamines afforded the corresponding bisallyloxyazetidinones; as the cis-cis diastereomers, exclusively obtained as a mixture of cis-syn-cis and cis-anti-cis. RCM of the latter using Grubbs' catalysts afforded the corresponding macrocyclic bisazetidinones in good yields. The cis-anti-cis bisazetidinones are readily identified by H-1 NMR using Eu(hfC)(3) chiral shift reagent.

  DOI：

  10.1021/jo9006392
• 作为产物：
  描述：

  邻丙烯基氧基苯甲醛 、 乙二胺 以 甲醇 为溶剂， 反应 2.0h， 以85%的产率得到compound
  参考文献：
  名称：

  Staudinger Ketene−Imine Cycloaddition, RCM Approach to Macrocrocyclic Bisazetidinones

  摘要：

  Application of Staudinger ketene-imine cycloaddition reaction to bis-o-allyloxyarylideneamines afforded the corresponding bisallyloxyazetidinones; as the cis-cis diastereomers, exclusively obtained as a mixture of cis-syn-cis and cis-anti-cis. RCM of the latter using Grubbs' catalysts afforded the corresponding macrocyclic bisazetidinones in good yields. The cis-anti-cis bisazetidinones are readily identified by H-1 NMR using Eu(hfC)(3) chiral shift reagent.

  DOI：

  10.1021/jo9006392

文献信息

• BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF
  申请人：HENKEL CORPORATION

  公开号：EP0743937A1

  公开（公告）日：1996-11-27
• US5514823A
  申请人：——

  公开号：US5514823A

  公开（公告）日：1996-05-07
• [EN] BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF<br/>[FR] BIS-(ALKYLSALICYLIDENE)ETHYLENE OU PHENYLENE-DIAMINES ET COMPLEXES DE METAUX TRANSITOIRES DE CES DERNIERES
  申请人：HENKEL CORPORATION

  公开号：WO1995021152A1

  公开（公告）日：1995-08-10

  (EN) Preparation of N,N'-bis(alkylsalicylidene)ethylene or phenylene diamines, and transition metal complexes thereof, particularly copper, and their use as an additive to diesel fuel to reduce soot formation in diesel exhaust.(FR) Cette invention concerne la préparation de N, N'-bis(alkylsalicylidène)éthylène ou phénylène-diamines et les complexes de métaux transitoires de ces dernières, notamment de cuivre, ainsi que leur utilisation comme additif pour carburant Diesel pour réduire la formation de suie dans l'échappement d'un moteur Diesel
• Staudinger Ketene−Imine Cycloaddition, RCM Approach to Macrocrocyclic Bisazetidinones
  作者：Yehia A. Ibrahim、Talal F. Al-Azemi、Mohamed D. Abd El-Halim、Elizabeth John

  DOI：10.1021/jo9006392

  日期：2009.6.5

  Application of Staudinger ketene-imine cycloaddition reaction to bis-o-allyloxyarylideneamines afforded the corresponding bisallyloxyazetidinones; as the cis-cis diastereomers, exclusively obtained as a mixture of cis-syn-cis and cis-anti-cis. RCM of the latter using Grubbs' catalysts afforded the corresponding macrocyclic bisazetidinones in good yields. The cis-anti-cis bisazetidinones are readily identified by H-1 NMR using Eu(hfC)(3) chiral shift reagent.