(E)-N-(3-methylindol-1-yl)propan-1-imine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (E)-N-(3-methylindol-1-yl)propan-1-imine
• 化学式: C₁₂H₁₄N₂
• 分子量: 186.25
• InChiKey: HAPDTGGOWRVVKA-MDWZMJQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  17.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS<br/>[FR] PROCEDE DE PREPARATION DE COMPOSES HETEROCYCLIQUES A SUBSTITUTION N-AMINO
  申请人：AVENTIS PHARMA INC

  公开号：WO2005035496A1

  公开（公告）日：2005-04-21

  An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an ambodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N-amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.

  本发明揭示并声明了一种制备N-氨基氮杂环化合物的改进工艺。在本发明的一种实施例中，通过N-取代和随后与酮类化合物反应形成一个肼酮，从相应的吲哚衍生物制备出式（VI）化合物。肼酮的进一步还原和随后与吡啶化合物偶联，得到式VI化合物或其适当的盐。
• Process for the preparation of N-amino substituted heterocyclic compounds
  申请人：Weiberth Franz

  公开号：US20050101654A1

  公开（公告）日：2005-05-12

  An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an embodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N-amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.

  本发明揭示并要求一种改进的制备N-氨基氮杂环化合物的工艺。在本发明的一种实施例中，通过N-氨化和随后与酮化合物反应形成一个肼酮的方式，从相应的吲哚衍生物制备公式（VI）的化合物。肼酮的进一步还原和随后与吡啶化合物偶联，得到公式VI的化合物或其适当的盐。
• RESIN DISPERSION AND RESIN PARTICLE
  申请人：Sanyo Chemical Industries, Ltd.

  公开号：EP1710272A1

  公开（公告）日：2006-10-11

  Disclosed are core-shell resin particles (C2) each comprising one or more film-like shell layers (P) comprising a first resin (a) and a core layer (Q) comprising a second resin (b). A core-shell resin particle (C2) is characterized in that the weight ratio between (P) and (Q) is from 0.1:99.9 to 70:30, the volatile content in the resin particle (C2) is not more than 2 weight %, and the resin (a) has an initial softening temperature of 40 to 270°C, a Tg of 20 to 250°C, a flow temperature of 60 to 300°C, and the difference of the Tg and the flow temperature in a range of 0 to 120°C. Said resin particles are excellent in electrostatic property, thermal storage stability and thermal properties, and exhibit a narrow particle diameter distribution.

  本发明公开了芯壳树脂颗粒（C2），每个芯壳树脂颗粒（C2）包括一个或多个由第一种树脂（a）组成的薄膜状外壳层（P）和由第二种树脂（b）组成的芯层（Q）。芯壳树脂颗粒（C2）的特征在于，(P)和(Q)的重量比为 0.1:99.9 至 70:30，树脂颗粒（C2）中的挥发物含量不超过 2 重量%，树脂(a)的初始软化温度为 40 至 270°C，Tg 为 20 至 250°C，流动温度为 60 至 300°C，Tg 和流动温度的差值范围为 0 至 120°C。所述树脂颗粒具有优异的静电性能、热储存稳定性和热性能，并呈现出较窄的颗粒直径分布。
• PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS
  申请人：Aventis Pharmaceuticals Inc.

  公开号：EP1678135B1

  公开（公告）日：2009-05-13
• US7112682B2
  申请人：——

  公开号：US7112682B2

  公开（公告）日：2006-09-26