(S)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-butyric acid benzyl ester | 187796-31-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (S)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-butyric acid benzyl ester
• 英文别名: benzyl (2S)-2,4-bis[[tert-butyl(dimethyl)silyl]oxy]butanoate
• CAS: 187796-31-2
• 化学式: C₂₃H₄₂O₄Si₂
• 分子量: 438.755
• InChiKey: RVGPIKFYUBSLAE-FQEVSTJZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.53
• 重原子数：
  29
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (S)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-butyric acid benzyl ester 在 palladium on activated charcoal 氢气 作用下， 以 二氯甲烷 、 乙酸乙酯 为溶剂， 反应 2.5h， 生成 tert-butyl (S)-2,4-di-tert-butyldimethylsilyloxybutanoate
  参考文献：
  名称：

  A New Efficient Synthesis of Nicotianamine and 2'-Deoxymugineic Acid

  摘要：

  Nicotianamine and 2'-deoxymugineic acid, phytosiderophores, have been efficiently synthesized, which will be suitable for large scale production of these plant physiologically important compounds. The synthetic method for 2',3 ''-dideoxy-3 ''-oxomugineic acid was also investigated.

  DOI：

  10.3987/com-96-s52
• 作为产物：
  描述：

  叔丁基二甲基氯硅烷 、 benzyl (S)-2,4-dihydroxybutanoate 在 咪唑 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 20.5h， 生成 (S)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-butyric acid benzyl ester
  参考文献：
  名称：

  A New Efficient Synthesis of Nicotianamine and 2'-Deoxymugineic Acid

  摘要：

  Nicotianamine and 2'-deoxymugineic acid, phytosiderophores, have been efficiently synthesized, which will be suitable for large scale production of these plant physiologically important compounds. The synthetic method for 2',3 ''-dideoxy-3 ''-oxomugineic acid was also investigated.

  DOI：

  10.3987/com-96-s52

文献信息

• A New Efficient Synthesis of Nicotianamine and 2'-Deoxymugineic Acid
  作者：Takayuki Shioiri、Naoko Irako、Sachiko Sakakibara、Fumiyoshi Matsuura、Yasumasa Hamada

  DOI：10.3987/com-96-s52

  日期：——

  Nicotianamine and 2'-deoxymugineic acid, phytosiderophores, have been efficiently synthesized, which will be suitable for large scale production of these plant physiologically important compounds. The synthetic method for 2',3 ''-dideoxy-3 ''-oxomugineic acid was also investigated.