2-(5-Methoxy-2-methyl-phenyl)-4,4-dimethyl-3-vinyl-cyclohex-2-enone | 217460-43-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(5-Methoxy-2-methyl-phenyl)-4,4-dimethyl-3-vinyl-cyclohex-2-enone
• 英文别名: 3-Ethenyl-2-(5-methoxy-2-methylphenyl)-4,4-dimethylcyclohex-2-en-1-one
• CAS: 217460-43-0
• 化学式: C₁₈H₂₂O₂
• 分子量: 270.371
• InChiKey: WTQLHVVJLQKATC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(5-Methoxy-2-methyl-phenyl)-4,4-dimethyl-3-vinyl-cyclohex-2-enone 在 四氯化钛 作用下， 反应 0.25h， 以83%的产率得到8,8,10a-Trimethyl-7,8,10,10a-tetrahydro-6H,9H-phenanthrene-3,5-dione
  参考文献：
  名称：

  The synthesis of quaternary carbon centers through cyclialkylations

  摘要：

  Treatment of conjugated dienone 1 with at strong Lewis acid at -78 degrees C produced a hydrophenanthrene with a newly created quaternary carbon. During this transformation the arene moiety becomes a dienone system. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)01931-5
• 作为产物：
  描述：

  2-(5-Methoxy-2-methyl-phenyl)-6,6-dimethyl-1-vinyl-cyclohex-2-enol 在 重铬酸吡啶 作用下， 生成 2-(5-Methoxy-2-methyl-phenyl)-4,4-dimethyl-3-vinyl-cyclohex-2-enone
  参考文献：
  名称：

  The synthesis of quaternary carbon centers through cyclialkylations

  摘要：

  Treatment of conjugated dienone 1 with at strong Lewis acid at -78 degrees C produced a hydrophenanthrene with a newly created quaternary carbon. During this transformation the arene moiety becomes a dienone system. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)01931-5

文献信息

• The synthesis of quaternary carbon centers through cyclialkylations
  作者：George Majetich、Jing Fang

  DOI：10.1016/s0040-4039(98)01931-5

  日期：1998.11

  Treatment of conjugated dienone 1 with at strong Lewis acid at -78 degrees C produced a hydrophenanthrene with a newly created quaternary carbon. During this transformation the arene moiety becomes a dienone system. (C) 1998 Elsevier Science Ltd. All rights reserved.