Ethyl 2-(2-bromoacetyl)hexanoate | 86578-53-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: Ethyl 2-(2-bromoacetyl)hexanoate
• CAS: 86578-53-2
• 化学式: C₁₀H₁₇BrO₃
• 分子量: 265.147
• InChiKey: OCNSNZLCXGLIOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ethyl 2-(2-bromoacetyl)hexanoate 反应 2.0h， 生成 3-丁基-4-羟基-2(5H)呋喃酮
  参考文献：
  名称：

  Synthesis of Peroxylactones Using Mn(III)-Catalyzed Aerobic Oxidation

  摘要：

  The aerobic oxidation of tetronic acid in the presence of 1,1-disubstituted alkenes afforded hydroperoxyethyl-peroxylactones, while a similar reaction using 3-alkyl-substituted tetronic acids gave stable crystalline peroxylactones in good to excellent yields. The oxidation using a stoichiometric amount of manganese(III) acetate did not give the bicyclic lactone but the ethenyland/or ethyl-tetronic acid derivatives.

  DOI：

  10.3987/com-11-12241
• 作为产物：
  描述：

  2-正丁基乙酰乙酸乙酯 在 溴 作用下， 以 氯仿 为溶剂， 生成 Ethyl 2-(2-bromoacetyl)hexanoate
  参考文献：
  名称：

  Synthesis of Peroxylactones Using Mn(III)-Catalyzed Aerobic Oxidation

  摘要：

  The aerobic oxidation of tetronic acid in the presence of 1,1-disubstituted alkenes afforded hydroperoxyethyl-peroxylactones, while a similar reaction using 3-alkyl-substituted tetronic acids gave stable crystalline peroxylactones in good to excellent yields. The oxidation using a stoichiometric amount of manganese(III) acetate did not give the bicyclic lactone but the ethenyland/or ethyl-tetronic acid derivatives.

  DOI：

  10.3987/com-11-12241

文献信息

• ORR, D. E.;MIAH, A. J., CHEM. AND IND., 1983, N 10, 392
  作者：ORR, D. E.、MIAH, A. J.

  DOI：——

  日期：——
• Synthesis of Peroxylactones Using Mn(III)-Catalyzed Aerobic Oxidation
  作者：Hiroshi Nishino、Md. Aminul Haque

  DOI：10.3987/com-11-12241

  日期：——

  The aerobic oxidation of tetronic acid in the presence of 1,1-disubstituted alkenes afforded hydroperoxyethyl-peroxylactones, while a similar reaction using 3-alkyl-substituted tetronic acids gave stable crystalline peroxylactones in good to excellent yields. The oxidation using a stoichiometric amount of manganese(III) acetate did not give the bicyclic lactone but the ethenyland/or ethyl-tetronic acid derivatives.