(1S,2R)-1,2-dihydrophenanthrene-1,2-diol | 82166-63-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: (1S,2R)-1,2-dihydrophenanthrene-1,2-diol
• CAS: 82166-63-0
• 化学式: C₁₄H₁₂O₂
• 分子量: 212.24
• InChiKey: FZOALBNXOKAOEW-KGLIPLIRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Novel polypeptides and methods for their use
  申请人：——

  公开号：US20030022335A1

  公开（公告）日：2003-01-30

  The invention provides an NDO or NDO related complex comprising at least one alpha-subunit polypeptide that comprises: 1) a substituted amino acid at the position corresponding to position 352 in NDO, 2) a substituted amino acid at the position corresponding to position 201, 202, 260, 316, 351, 358, 362, or 366 in NDO, or 3) a substituted amino acid at the position corresponding to position 352 in NDO, and a substituted amino acid at the position corresponding to position 201, 202, 260, 316, 351, 358, 362, or 366 in NDO; or a catalytically active fragment thereof. The invention also provides DNA encoding such polypeptides, host cells augmented by such DNA, and methods for using the enzymes or host cells to provide useful and novel synthons. The invention also provides novel compounds prepared with the complexes or methods of the invention.

  本发明提供了一种包含至少一个α-亚基多肽的NDO或NDO相关复合物，其中该α-亚基多肽包括：1）在与NDO的352位相对应的位置上的取代氨基酸，2）在与NDO的201、202、260、316、351、358、362或366位相对应的位置上的取代氨基酸，或3）在与NDO的352位相对应的位置上的取代氨基酸和在与NDO的201、202、260、316、351、358、362或366位相对应的位置上的取代氨基酸；或其催化活性片段。本发明还提供了编码这种多肽的DNA，通过这种DNA增强的宿主细胞以及使用这些酶或宿主细胞提供有用和新颖合成物的方法。本发明还提供了使用该复合物或本发明的方法制备的新型化合物。
• US6794167B2
  申请人：——

  公开号：US6794167B2

  公开（公告）日：2004-09-21
• [EN] NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE<br/>[FR] NOUVELLE NAPHTALENE DIOXYGENASE (NDO) ET SON UTILISATION
  申请人：UNIV IOWA RES FOUND

  公开号：WO2000037480A1

  公开（公告）日：2000-06-29

  The invention provides an NDO or NDO related complex comprising at least one alpha-subunit polypeptide that comprises: (1) a substituted amino acid at the position corresponding to position 352 in NDO, (2) a substituted amino acid at the position corresponding to position 201, 202, 260, 316, 351, 358, 362, or 366 in NDO, or (3) a substituted amino acid at the position corresponding to position 352 in NDO, and a substituted amino acid at the position corresponding to position 352 in NDO, and a substituted amiro acid at the position corresponding to position 201, 202, 260, 316, 351, 358, 362, or 366 in NDO; or a catalytically active fragment thereof. The invention also provides DNA encoding such polypeptides, host cells augmented by such DNA, and methods for using the enzymes or host cells to provide useful and novel synthons. The invention also provides novel compounds prepared with the complexes or methods of the invention.