3-乙氧基-4-氨基偶氮苯 | 125804-07-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-乙氧基-4-氨基偶氮苯
• 英文名称: Tridecyl ethylhexanoate
• 英文别名: tridecyl 2-ethylhexanoate
• CAS: 125804-07-1
• 化学式: C₂₁H₄₂O₂
• 分子量: 326.6
• InChiKey: BFRLRPIMWQKGTM-UHFFFAOYSA-N

物化性质

• 沸点：
  368.2±10.0 °C(Predicted)
• 密度：
  0.861±0.06 g/cm3(Predicted)
• LogP：
  9.291 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• UV ABSORBER FORMULATIONS
  申请人：Acker Stephanie

  公开号：US20100111884A1

  公开（公告）日：2010-05-06

  Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R 1 and R 2 , independently of one another, are C 3 -C 18 alkyl; C 2 -C 18 alkenyl; a radical of the formula —CH 2 —CH(OH)—CH 2 —O-T 1 ; or R 1 and R 2 are a radical of the formula (4a); R 7 is a direct bond; a straight-chain or branched C 1 -C 4 alkylene radical or a radical of the formula (I) or (II); R 8 , R 9 and R 10 , independently of one another, are C 1 -C 18 alkyl; C 1 -C 18 alkoxy or a radical of the formula (III); R 11 is C 1 -C 5 alkyl; m 1 is a number from 1 to 4; p 1 is 0; or a number from 1 to 5; A 1 is a radical of the formula (1b), (1c) or (1d); R 3 is hydrogen; C 1 -C 10 alkyl; —(CH 2 CHR 5 —O)n 1 -T 2 ; or —CH 2 —CH(—OH)—CH 2 —O-T 2 ; R 4 is hydrogen; M; C 1 -C 5 alkyl; or —(CH 2 )m 2 —O-T 3 ; R 5 is hydrogen; or methyl; T 1 , T 2 and T 3 independently from each other are hydrogen; or C 1 -C 18 alkyl; Q 1 is C 1 -C 18 alkyl, M is a metal cation; m 2 is 1 to 4; and n 1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.

  本发明公开了一种紫外线过滤组合物，包括（a）式（1）的有机紫外线吸收剂，其中R1和R2独立地是C3-C18烷基；C2-C18烯基；式—CH2—CH（OH）—CH2—O-T1的基团；或者R1和R2是式（4a）的基团；R7是直链或支链C1-C4烷基、式（I）或（II）的基团；R8、R9和R10独立地是C1-C18烷基、C1-C18烷氧基或式（III）的基团；R11是C1-C5烷基；m1是1至4的数字；p1是0或1至5的数字；A1是式（1b）、（1c）或（1d）的基团；R3是氢、C1-C10烷基、式—（CH2CHR5—O）n1-T2或式—CH2—CH（—OH）—CH2—O-T2；R4是氢、M、C1-C5烷基或式—（CH2）m2—O-T3；R5是氢或甲基；T1、T2和T3互相独立地是氢或C1-C18烷基；Q1是C1-C18烷基，M是金属阳离子；m2是1至4的数字；n1是1-16，（b）二甲基辛酰胺，（c）化妆品可接受载体；和水。
• POLYISOBUTENE FOR USE IN TREATMENT OR PREVENTION OF INFECTION BY ARTHROPODS
  申请人：Oystershell NV

  公开号：EP3785540A1

  公开（公告）日：2021-03-03

  The present invention provides polyisobutene and composition thereof and their use medical, insecticidal, prophylactic or therapeutic substances for the treatment or prevention of infection or infestation by arthropods. More specifically, the invention relates to the use of polyisobutene and compositions thereof for treatment of lice infections.

  本发明提供了聚异丁烯及其组合物，以及它们用于治疗或预防节肢动物感染或侵扰的医疗、杀虫、预防或治疗物质。更具体地说，本发明涉及聚异丁烯及其组合物治疗虱子感染的用途。
• Surfactant-free, water-free formable composition and breakable foams and their uses
  申请人：Tamarkin Dov

  公开号：US10029013B2

  公开（公告）日：2018-07-24

  A substantially surface active agent-free and foam adjuvant-free composition which includes a hydrophobic solvent, a wax and a propellant. A substantially surface active agent-free and foam adjuvant-free composition, further comprising, a tetracycline antibiotic, or one or More other active agents. A method of treatment, using a substantially surface active agent-free and substantially foam adjuvant-free composition.

  一种基本不含表面活性剂和泡沫佐剂的组合物，包括疏水性溶剂、蜡和推进剂。一种基本不含表面活性剂和泡沫佐剂的组合物，进一步包括四环素抗生素或一种或多种其他活性剂。一种使用基本不含表面活性剂和基本不含泡沫佐剂的组合物的治疗方法。
• Topical tetracycline compositions
  申请人：Foamix Pharmaceuticals Ltd.

  公开号：US10086080B2

  公开（公告）日：2018-10-02

  A topical therapeutic hydrophobic breakable composition includes a carrier comprising (a) about 60% to about 99% by weight of at least one hydrophobic oil; (b) at least one viscosity-modifying agents selected from the group consisting of a fatty alcohol, a fatty acid and a wax; and (c) a tetracycline antibiotic, characterized in that at least part of the tetracycline antibiotic is suspended in the composition; the viscosity of the composition is at least about 30% higher than the viscosity of the carrier without the tetracycline antibiotic; and is higher than the viscosity of the hydrophobic oil and the tetracycline antibiotic without the viscosity modifying agents; and the amount of viscosity modifying agents can optionally be reduced by at least an amount by weight that would have increased the viscosity of the carrier without the tetracycline antibiotic by at least 30%; wherein the tetracycline is chemically stable in the composition for at least six months; wherein more than about 90% of the tetracycline has not broken down; wherein when packaged in an aerosol container to which is added a liquefied or compressed gas propellant the composition affords upon release from the container a breakable foam of at least good quality that breaks easily upon application of shear force.

  一种局部治疗疏水性可破壁组合物包括一种载体，该载体包含(a) 至少一种疏水性油重量的约 60%至约 99%；(b) 至少一种粘度调节剂，该粘度调节剂选自由脂肪醇、脂肪酸和蜡组成的组；(c) 四环素类抗生素，其特征在于至少部分四环素类抗生素悬浮在组合物中；组合物的粘度比不含四环素类抗生素的载体的粘度高至少约 30%；比不含粘度调节剂的疏水油和四环素类抗生素的粘度高；其中四环素在组合物中的化学稳定性至少为 6 个月；其中超过约 90% 的四环素没有分解； 当包装在添加了液化或压缩气体推进剂的气雾剂容器中时，该组合物从容器中释放出来时，可产生至少质量良好的易破碎泡沫，在施加剪切力时很容易破碎。
• Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
  申请人：Foamix Pharmaceuticals Ltd.

  公开号：US10137200B2

  公开（公告）日：2018-11-27

  A substantially surface active agent free composition which includes a hydrophobic solvent, and/or a petrolatum, a paraffin wax and/or a fatty alcohol, a fatty acid and/or a wax and/or shea butter, with and without a propellant. A substantially surface active agent free composition, further comprising, a tetracycline antibiotic, or a vitamin D derivative, or one or more other active agents. A method of treatment using a substantially surface active agent free composition.

  一种基本不含表面活性剂的组合物，包括疏水性溶剂和/或凡士林油、石蜡和/或脂肪醇、脂肪酸和/或蜡和/或乳木果油，含或不含推进剂。一种基本不含表面活性剂的组合物，进一步包含四环素抗生素，或维生素 D 衍生物，或一种或多种其他活性剂。一种使用基本不含表面活性剂的组合物进行治疗的方法。