3-[3-(2-acetylamino-ethyl)-5-methoxy-indol-1-yl]-propionic acid | 70645-76-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-[3-(2-acetylamino-ethyl)-5-methoxy-indol-1-yl]-propionic acid
• 英文别名: 3-[3-(2-Acetamidoethyl)-5-methoxy-1H-indol-1-yl]propanoic acid；3-[3-(2-acetamidoethyl)-5-methoxyindol-1-yl]propanoic acid
• CAS: 70645-76-0
• 化学式: C₁₆H₂₀N₂O₄
• 分子量: 304.346
• InChiKey: XOWGIKFUOWAIAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  80.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Melatonin monoclonal antibody, detection, methods and uses thereof
  申请人：SALIMETRICS, LLC

  公开号：US10787512B2

  公开（公告）日：2020-09-29

  The invention provides monoclonal antibodies and fragments thereof that specifically bind to melatonin. Also provided are heavy chain variable region (VH) and light chain variable region (VL) sequences of such monoclonal antibodies and fragments thereof. Further provided are melatonin conjugates, and methods and uses, for example, determining, detecting, measuring, screening for, analyzing and monitoring an amount of melatonin in a sample.

  本发明提供了与褪黑激素特异性结合的单克隆抗体及其片段。还提供了此类单克隆抗体及其片段的重链可变区（VH）和轻链可变区（VL）序列。本发明还提供了褪黑素共轭物，以及确定、检测、测量、筛选、分析和监测样品中褪黑素含量的方法和用途。
• [EN] MELATONIN MONOCLONAL ANTIBODY, DETECTION, METHODS AND USES THEREOF<br/>[FR] ANTICORPS MONOCLONAL DE MÉLATONINE, DÉTECTION, PROCÉDÉS ET UTILISATIONS DE CELUI-CI
  申请人：SALIMETRICS LLC

  公开号：WO2014144725A2

  公开（公告）日：2014-09-18

  The invention provides monoclonal antibodies and fragments thereof that specifically bind to melatonin. Also provided are heavy chain variable region (VH) and light chain variable region (VL) sequences of such monoclonal antibodies and fragments thereof. Further provided are melatonin conjugates, and methods and uses, for example, determining, detecting, measuring, screening for, analyzing and monitoring an amount of melatonin in a sample.