3-氧代-6-乙酰氨基己酸酯 | 59403-50-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 中文名称: 3-氧代-6-乙酰氨基己酸酯
• 英文名称: 6-Acetamido-2-oxohexanoic acid
• CAS: 59403-50-8
• 化学式: C₈H₁₃NO₄
• 分子量: 187.19
• InChiKey: NGCXIFFZXAZRAF-UHFFFAOYSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  83.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Process for producing 5-aminopentanoate empolying a recombinant microorganism
  申请人：Metabolic Explorer

  公开号：EP2647718A2

  公开（公告）日：2013-10-09

  The present invention concerns a method for the biological preparation of 5-aminopentanoate comprising culturing a microorganism genetically modified for the bioproduction of 5-aminopentanoate, wherein the microorganism comprises a metabolic pathway for conversion of lysine or 2-oxoadipate into 5-aminopentanoate.

  本发明涉及一种生物制备 5-氨基戊酸盐的方法，该方法包括培养一种为生物生产 5-氨基戊酸盐而转基因的微生物，其中该微生物具有将赖氨酸或 2-氧代己二酸盐转化为 5-氨基戊酸盐的代谢途径。
• Metabolomics-Based Identification of Disease-Causing Agents
  申请人：Skolnick Jeffrey

  公开号：US20110246081A1

  公开（公告）日：2011-10-06

  A method, computer-readable medium, and system for identifying one or more metabolites associated with a disease, comprising: comparing gene expression data from diseased cells to gene expression data from control cells in order to deduce genes that are differentially-regulated in the diseased cells relative to the control cells; based on enzyme function and pathway data for all human metabolites that utilize the genes that are differentially-regulated in the disease cells, identifying one or more metabolites whose intracellular levels are higher or lower in diseased cells than in control cells, and thereby associating the one or more metabolites with the disease.
• US9673030B2
  申请人：——

  公开号：US9673030B2

  公开（公告）日：2017-06-06
• [EN] METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS<br/>[FR] IDENTIFICATION D'AGENTS PROVOQUANT UNE MALADIE BASÉE SUR LA MÉTABOLOMIQUE
  申请人：GEORGIA TECH RES INST

  公开号：WO2009052186A1

  公开（公告）日：2009-04-23

  A method, computer-readable medium, and system for identifying one or more metabolites associated with a disease, comprising: comparing gene expression data from diseased cells to gene expression data from control cells in order to deduce genes that are differentially-regulated in the diseased cells relative to the control cells; based on enzyme function and pathway data for all human metabolites that utilize the genes that are differentially-regulated in the disease cells, identifying one or more metabolites whose intracellular levels are higher or lower in diseased cells than in control cells, and thereby associating the one or more metabolites with the disease.