3-氧代丙戊酸 | 60113-81-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 中文名称: 3-氧代丙戊酸
• 英文名称: 3-Oxovalproic acid
• 英文别名: 3-oxo-2-propylpentanoic acid
• CAS: 60113-81-7
• 化学式: C₈H₁₄O₃
• 分子量: 158.19
• InChiKey: PPYHXKUZTSZTQU-UHFFFAOYSA-N

物化性质

• 沸点：
  267.9±23.0 °C(Predicted)
• 密度：
  1.035±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2918300090

反应信息

• 作为反应物：
  描述：

  3-氧代丙戊酸 、 α-溴-2,3,4,5,6-五氟甲基苯酸酯 生成 (2,3,4,5,6-pentafluorophenyl)methyl 3-oxo-2-propylpentanoate
  参考文献：
  名称：

  KASSAHUN, KELEM;FARRELL, KEVIN;ZHENG, JIAOJIAO;ABBOTT, FRANK, J. CHROMATOGR. BIOMED. APPL., 527,(1990) N, C. 327-341

  摘要：

  DOI：

文献信息

• Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0083690A1

  公开（公告）日：1983-07-20

  A polyamide acid composition for preparing a polyimide which can extend the pot life of the composition comprising a solution of a polyamide acid in an organic solvent, the polyamide acid being a precursor of the polyimide, a dehydrating agent, a catalyst and a pot life extending agent which can lower a rate of conversion of the polyamide acid to the plyimide, and the process for preparing the polyimide from said polyamide acid composition. According to the present invention the pot life can be extremely extended to give the composition an enough flowability for a long time without reducing the excellent properties such as a heat resistance and an electric insulation of the obtained polyimide.

  一种用于制备聚酰亚胺的聚酰胺酸组合物，可延长组合物的固化寿命，该组合物包括聚酰胺酸在有机溶剂中的溶液（聚酰胺酸是聚酰亚胺的前体）、脱水剂、催化剂和可降低聚酰胺酸转化为聚酰亚胺的速率的固化寿命延长剂，以及用上述聚酰胺酸组合物制备聚酰亚胺的工艺。根据本发明，可以极大地延长聚酰亚胺的罐装寿命，使该组合物具有足够长的流动性，而不会降低所得聚酰亚胺的优异性能，如耐热性和电绝缘性。
• Method of therapeutic drug monitoring
  申请人：Bayer HealthCare, LLC

  公开号：EP1938750A2

  公开（公告）日：2008-07-02

  A method of using a diffusion-based, continuous-monitoring system to monitor the effectiveness of delivering a drug includes creating and maintaining a diffusion channel in an area of skin. The levels of the drug, metabolite, or affected substance of the drug are continuously monitored in the area of the skin for a desired duration via a diffusion-based, continuous-monitoring device. The levels of the drug, the metabolite, or affected substance are analyzed to determine the effectiveness of delivering the therapeutic drug.

  一种使用基于扩散的连续监测系统监测给药效果的方法包括在皮肤区域创建并维持一个扩散通道。通过基于扩散的连续监测装置，在所需时间内连续监测皮肤区域的药物、代谢物或药物受影响物质的水平。对药物、代谢物或受影响物质的含量进行分析，以确定输送治疗药物的有效性。
• TATSUHARA, TOHORU;MURO, HIDEKI;MATSUDA, YOSHIHIRO;IMAI, YOUKO, J. CHROMATOGR., 399,(1987) 183-195
  作者：TATSUHARA, TOHORU、MURO, HIDEKI、MATSUDA, YOSHIHIRO、IMAI, YOUKO

  DOI：——

  日期：——
• PROCESS TO SEPARATE LINEAR ALKYL 5-FORMYLVALERATE
  申请人：DSM IP Assets B.V.

  公开号：EP1169290B1

  公开（公告）日：2003-11-12
• METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS)
  申请人：Oregon Institute of Science and Medicine

  公开号：US20190391092A1

  公开（公告）日：2019-12-26

  A method for constructing a metabolic profile of a mammalian (such as a human) subject from one of more urine samples from the subject uses magnetic resonance mass spectrometry (MRMS) for the rapid and inexpensive quantitative measurement of at least 4,000 urinary chemical substances in a single analysis. The method for metabolic profiling measures thousands of urinary substances in a urine sample from a mammalian subject in a single assay. Many of these substances can be of mammalian metabolic origin. The measurements of types and amounts of urinary substances can be correlated to assessments of present or future health of the subject.