1H-Indole-3-acetic acid, 2,3-dihydro-4-hydroxy- | 141102-32-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1H-Indole-3-acetic acid, 2,3-dihydro-4-hydroxy-
• 英文别名: 2-(4-hydroxy-2,3-dihydro-1H-indol-3-yl)acetic acid
• CAS: 141102-32-1
• 化学式: C₁₀H₁₁NO₃
• 分子量: 193.2
• InChiKey: HQNTULMVBFWRNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• NATURAL SKIN WHITENER: 4-HYDROXY-OXINDOLE-3-ACETIC ACID
  申请人：WILLE, Jr. John Jacob

  公开号：US20100158842A1

  公开（公告）日：2010-06-24

  A cosmetic and dermatological composition comprises 2, 3-dihydro-4-hydroxy-2-oxo-1-H-indole-3-acetic acid (4-hydroxy-1-oxindole-3-acetic acid) as an active ingredient for use as a melanin inhibitor and as an anti-tyrosinase enzyme inhibitor. This composition is excellent as a skin whitening agent. Since it also has potent antioxidant and anti-irritant activities it is useful in a cosmetic composition for improving hyperpigmentation disorders of the skin.