3-氨基甲氧基丁基氨基甲酸酯 | 5952-27-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3-氨基甲氧基丁基氨基甲酸酯
• 英文名称: 1,3-Bis-carbamoyloxy-butan
• 英文别名: 1.3-Butylenglykol-dicarbamat；1,3-bis-carbamoyloxy-butane；3-Methyl-2,6-dioxa-heptandisaeure-diamid；1,3-Bis(carbamoyloxy)butane；3-carbamoyloxybutyl carbamate
• CAS: 5952-27-2
• 化学式: C₆H₁₂N₂O₄
• 分子量: 176.172
• InChiKey: ZNAVBUIWPSAZNF-UHFFFAOYSA-N

物化性质

• 熔点：
  150-152 °C
• 沸点：
  431.4±28.0 °C(Predicted)
• 密度：
  1.238±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-氨基甲氧基丁基氨基甲酸酯 生成 4-甲基-1,3-二氮杂环己烷-2-酮 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  A Hungarian example for handsearching specialized national healthcare journals of small countries for controlled trials. Is it worth the trouble?

  摘要：

  AbstractThe objective of this study was to determine whether a Hungarian language journal of clinical neuroscience, which is not indexed in medline, contains any reports of randomized or quasi‐randomized clinical trials that are not also reported in medline‐indexed publications. A cover‐to‐cover handsearch was performed of the journal Clinical Neuroscience/Ideggyógyászati Szemle, the official journal of Hungarian societies of neurology, neurosurgery, psychiatry and related clinical neurosciences, from its first volume in 1950 to the end of 1998; and a search of medline for other reports of the trials identified. Clinical trials in which patients were allocated to interventions by randomized, quasi‐randomized or possibly randomized means were identified. Controlled trials were tabulated and coded as randomized controlled trials or controlled clinical trials according to the definitions of the Handsearch Manual of the Cochrane Collaboration. We identified three randomized and eight quasi‐randomized trials. Six of the 11 trials were not reported in medline indexed publications.In conclusion, to obtain a comprehensive controlled trials register, specialized healthcare journals printed in small numbers in the national languages of small countries should be searched.

  DOI：

  10.1046/j.1365-2532.2000.00280.x
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氨 、 水 作用下， 生成 3-氨基甲氧基丁基氨基甲酸酯
  参考文献：
  名称：

  N-Carboalkoxy Derivatives of Procaine

  摘要：

  DOI：

  10.1021/ja01133a003

文献信息

• DE754369
  申请人：——

  公开号：——

  公开（公告）日：——
• DE501852
  申请人：——

  公开号：——

  公开（公告）日：——
• DE713467
  申请人：——

  公开号：——

  公开（公告）日：——
• Urea derivative of the 1.3-butylene-glycol and process of preparing them
  申请人：GEN ANILINE WORKS INC

  公开号：US01817992A1

  公开（公告）日：1931-08-11
• Preparation of organic dicarbamates
  申请人：BERKELEY CHEMICAL CORP

  公开号：US02837560A1

  公开（公告）日：1958-06-03