癸二酸二戊酯 | 6819-09-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 癸二酸二戊酯
• 英文名称: dipentyl sebacate
• 英文别名: decanedioic acid dipentyl ester；Diamylsebacat；Sebacinsaeurediamylester；Dipentylsebacat；Decandisaeure-dipentylester；diamyl sebacate；dipentyl decanedioate
• CAS: 6819-09-6
• 化学式: C₂₀H₃₈O₄
• 分子量: 342.519
• InChiKey: WZURZWRVLHOHAS-UHFFFAOYSA-N

物化性质

• 保留指数：
  2360

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  24
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  癸二酸 、 戊醇 在 6H₂O*Na₃[AlMo₆O₁₈(OH)6] 作用下， 以79%的产率得到癸二酸二戊酯
  参考文献：
  名称：

  用无机配体负载催化剂将生物质衍生的二元酸转化为二酯：合成、优化、表征

  摘要：

  已经进行了几次尝试以从酯化反应中获得脂肪族二羧酸二酯，以开发生物质衍生的平台分子和绿色制造工艺。本文首先报道了一种 Anderson 型多金属氧酸盐 Na 3 (H 2 O) 6 [AlMo 6 O 18 (OH) 6 ] 作为二羧酸合成二酯的催化剂，具有良好的产率和选择性以 1 H 和 13 C 为特征。响应面法 (RSM) 与意愿函数法相结合，确定最佳操作条件，最大琥珀酸二丙酯产率 (77 ± 2.5%) 的最佳反应参数确定为 1.19 mol.% 催化剂负载，4.9:1 丙醇/琥珀酸比，113 °C 和 9.6 小时。即使经过 6 次酯化循环，也进行了三批催化剂回收试验，产率达到 78-75%。此外，为了研究底物范围，增加了底物碳链，获得了满意的结果，所有产品均通过 1 H 和 13 C 核磁共振光谱进行了表征。

  DOI：

  10.1007/s11164-021-04570-z

文献信息

• [EN] PROCESS FOR PREPARING AN ESTER<br/>[FR] PROCÉDÉ POUR LA PRÉPARATION D'UN ESTER
  申请人：SHELL INT RESEARCH

  公开号：WO2011015385A1

  公开（公告）日：2011-02-10

  A process for preparing an ester of formula (I): R3CH2- (CR1R2)n-CH2-O-CO-(CR1R2)n-CH2R3 (I) wherein n is 1-3 and R1 and R2 are each, independently, a hydrogen atom or a carbon-linked organic group and R3 is a carbon-linked organic group, by hydrogenation of a reactant selected from: (a) a lactone of formula (II) wherein n is 1-3 and R1 and R2 are each, independently, a hydrogen atom or a carbon-linked organic group and R3 is a carbon-linked organic group; (b) an ester of a carboxylic acid of formula (III) R4-O-CO- (CR1R2)n-CO-R3 (III) wherein n is 1-3 and R1 and R2 are each, independently, a hydrogen atom or a carbon-linked organic group and R3 and R4 are a carbon-linked organic group; and c) a carboxylic acid of formula (IV) H-O-CO- (CR1R2)n-CO-R3 (IV) wherein n is 1-3 and R1 and R2 are each, independently, a hydrogen atom or a carbon-linked organic group and R3 is a carbon-linked organic group; which process involves contacting the reactant with a heterogeneous catalyst comprising a hydrogenating metal in the presence of hydrogen, wherein the catalyst is a zeolite-free heterogeneous catalyst comprising a hydrogenating metal supported on a metal oxide or a mixed oxide.

  制备式(I)酯的过程：R3CH2- (CR1R2)n-CH2-O-CO-(CR1R2)n-CH2R3 (I)，其中n为1-3，R1和R2分别独立地为氢原子或碳链有机基团，R3为碳链有机基团，通过选择的反应物的加氢制备：(a)式(II)内酯，其中n为1-3，R1和R2分别独立地为氢原子或碳链有机基团，R3为碳链有机基团；(b)式(III)羧酸酯，其中n为1-3，R1和R2分别独立地为氢原子或碳链有机基团，R3和R4为碳链有机基团；和(c)式(IV)羧酸，其中n为1-3，R1和R2分别独立地为氢原子或碳链有机基团，R3为碳链有机基团；该过程涉及将反应物与含有氢化金属的非均相催化剂接触，在氢气存在下，其中催化剂是一种不含沸石的非均相催化剂，包括负载在金属氧化物或混合氧化物上的氢化金属。
• Slow release pesticidal composition and control device, its preparation and its use
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0090446A2

  公开（公告）日：1983-10-05

  Slow release pesticidal composition comprising an intimate admixture of (a) a solid polymeric macromolecular substance, (b) a contact-pesticide having arthropodicidal action, and (c) a component acting as a carrier for the contact-pesticide, which component is incompatible with the solid polymeric marcomolecular substance.

  缓释杀虫组合物，包括以下物质的亲密混合物：(a) 一种固体聚合物大分子物质；(b) 一种具有杀节肢动物作用的接触型杀虫剂；(c) 一种用作接触型杀虫剂载体的成分，该成分与固体聚合物大分子物质不相容。
• Animal collar
  申请人：SANDOZ AG

  公开号：EP0095870A1

  公开（公告）日：1983-12-07

  An animal collar is provided comprising an elongate flexible strap (2) preferably of plastics material which may contain an ectoparasiticide. At one end of the strap fastening means (4) are provided having a passageway (10) with spaced apart opposing walls (12, 14) extending parallel to the strap through which the other end of the strap may be passed to form a loop. The passageway is provided with a hole (16) in its wall in which one of a number of projections (8) on the strap may be located to secure the loop. The strap is further provided with an extendable portion (70) which by means of frangible elements holding the ends of the slits in the strap together enables the strap to be lengthened increasing the loop size but maintaining an integral loop when a predetermined choking tension is applied to the loop breaking some of the frangible elements.

  一种动物项圈包括一条长的柔性带子（2），该带子最好是塑料材质的，其中可能含有外寄生虫杀虫剂。在带子的一端有紧固装置（4），紧固装置有一个通道（10），通道壁（12、14）与带子平行延伸，带子的另一端可以穿过通道形成一个环。通道的壁上有一个孔 (16)，带子上的多个凸起 (8) 中的一个可位于该孔中以固定环。带子上还有一个可延伸部分（70），通过将带子上狭缝的两端固定在一起的易碎元件，当对带子施加预定的窒息张力使一些易碎元件断裂时，可将带子拉长，增加环的尺寸，但保持一个完整的环。
• A pesticidal article
  申请人：THE WELLCOME FOUNDATION LIMITED

  公开号：EP0122605A2

  公开（公告）日：1984-10-24

  At least some of the bristles or teeth of a brush or comb are made of a polymeric material comprising a pesticide which can bloom to the surface of the material. A dog or other animal can thereby be treated against ectoparasites at the same time as being groomed. Pesticides which might react adversely with one another may be separated in different bristles. Suitable pesticides include pyrethroids and organophosphates. Suitable polymeric materials include PVC.

  刷子或梳子的刷毛或梳齿至少有一部分是由聚合材料制成的，这种材料含有杀虫剂，可以在材料表面绽放。这样，狗或其他动物就可以在梳理毛发的同时得到外寄生虫的治疗。可能会相互产生不良反应的杀虫剂可以分装在不同的刷毛中。合适的杀虫剂包括拟除虫菊酯类和有机磷酸酯类。合适的聚合材料包括聚氯乙烯。
• Insect control device for livestock containing fenthion
  申请人：MILES INC.

  公开号：EP0400438A1

  公开（公告）日：1990-12-05

  Annoying insects are controlled by attaching an insect control device to the body of the animal to be treated. The insect control device is a molded article, preferably in the form of an ear tag, which has been formed from a mixture of fenthion and polyvinyl chloride. In a preferred embodiment, the fenthion is used in combination with coumaphos. The fenthion is generally used in an amount such that it represents from about 5 to about 30 wt% of the insect control device. When used in combination with coumaphos, the fenthion is generally present in an amount of from about 5 to about 30 wt% and coumaphos is generally used in an amount such that from about 5 to about 30 wt% of the device is coumaphos. A plasticizer is not required to make the insect control device of the present invention but such plasticizer may optionally be used. Other materials such as lubricants, pigments, stabilizers, etc. may also be included in minor amounts. The device may be formed by any appropriate technique but injection molding has been found to be particularly advantageous.

  通过在待处理的动物身上安装昆虫控制装置来控制恼人的昆虫。昆虫控制装置是一种模制件，最好是耳标形式，由倍硫磷和聚氯乙烯混合物制成。在一个优选的实施方案中，倍硫磷与杀扑磷结合使用。倍硫磷的用量一般占昆虫控制装置的 5%至 30%。当倍硫磷与杀虫双结合使用时，倍硫磷的用量一般为约 5 至约 30 wt%，杀虫双的用量一般为杀虫双装置的约 5 至约 30 wt%。制造本发明的昆虫控制装置不需要增塑剂，但可以选择使用增塑剂。其他材料如润滑剂、颜料、稳定剂等也可以少量加入。该装置可以通过任何适当的技术成型，但注塑成型尤其有利。