4-Oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 7-oxo- | 1824201-61-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-Oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 7-oxo-
• 英文别名: 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• CAS: 1824201-61-7
• 化学式: C₆H₅NO₄
• 分子量: 155.11
• InChiKey: GLLGNLCYQGEJAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• STABLE COMPOSITIONS OF OXAPENEM-3-CARBOXYLIC ACIDS BY CO-LYOPHILISATION WITH PHARMACEUTICAL CARRIERS
  申请人：Amura Limited

  公开号：EP1326608A1

  公开（公告）日：2003-07-16
• [EN] STABLE COMPOSITIONS OF OXAPENEM-3-CARBOXYLIC ACIDS BY CO-LYOPHILISATION WITH PHARMACEUTICAL CARRIERS<br/>[FR] COMPOSITIONS STABLES D'ACIDES OXAPENEME-3-CARBOXYLIQUES PAR CO-LYOPHILISATION AVEC DES EXCIPIENTS PHARMACEUTIQUES
  申请人：AMURA LTD

  公开号：WO2002032424A1

  公开（公告）日：2002-04-25

  According to the present invention there is provided a pharmaceutical composition comprising a co-lyophilizate of: a pharmaceutical carrier; and an active ingredient of formulae I and II or a pharmaceutically acceptable salt thereof, wherein R?1 and R2¿, independently of one another, denote hydrogen, or pharmaceutically acceptable groups which have 1 to 10 carbon atoms and are bonded to the remaining part of the molecule via carbon-carbon single bonds and in which R?3, R4 and R5¿, independently of one another, denote pharmaceutically acceptable groups which are bonded to the exocyclic, allylic carbon atom via carbon atoms.