N-(2-diethylamino-ethyl)-methanesulfonamide | 88334-83-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-(2-diethylamino-ethyl)-methanesulfonamide
• 英文别名: N-(2-Diaethylamino-aethyl)-methansulfonamid；N-[2-(Diethylamino)ethyl]methanesulfonamide
• CAS: 88334-83-2
• 化学式: C₇H₁₈N₂O₂S
• mdl: MFCD11704486
• 分子量: 194.298
• InChiKey: XAFUIIMJQXXJPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  57.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲基磺酰氯 、 N,N-二乙基乙二胺 在 乙醚 作用下， 生成 N-(2-diethylamino-ethyl)-methanesulfonamide
  参考文献：
  名称：

  The Synthesis of N,N-Bis-(β-diethylaminoethyl)-amine and Some N-Substituted Alkanesulfonamides

  摘要：

  DOI：

  10.1021/ja01630a100

文献信息

• [EN] 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF<br/>[FR] 19-NOR-STÉROÏDES NEUROACTIFS ET PROCÉDÉS D'UTILISATION DE CEUX-CI
  申请人：SAGE THERAPEUTICS INC

  公开号：WO2014169836A1

  公开（公告）日：2014-10-23

  Provided herein are 3,3-disubstituted19-nor-steroidal compounds according to Formula(I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions,for example, treatment of sleep disorders, mood disorders,schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders,personality disorders,autism spectrum disorders, pain,traumatic brain injury, vascular diseases,substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.

  根据以下公式(I)，提供了3,3-二取代19-去甲类固醇化合物及其药物组合物。这些化合物被认为对预防和治疗各种与中枢神经系统相关的疾病有用，例如治疗睡眠障碍、情绪障碍、精神分裂症谱系障碍、记忆和/或认知障碍、运动障碍、人格障碍、自闭症谱系障碍、疼痛、创伤性脑损伤、血管疾病、物质滥用障碍和/或戒断综合征、耳鸣、癫痫持续状态。
• Method For Directly Producing Fine-Particle Diketopyrrolopyrrol Pigments
  申请人：Ganschow Matthias

  公开号：US20100121053A1

  公开（公告）日：2010-05-13

  The invention relates to a method for directly producing fine-particle 1,4-diketopyrrolo[3,4-c]pyrrols of formula (1), wherein R 1a , R 1b , R 2a and R 2b independently represent hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, cyano or phenyl, said compounds being characterized by a maximum frequency distribution between 20 and 120 nm. According to the method, nitriles are reacted with succinic acid esters or lactames or enamines in an alkali medium to form a pigment salt, and then protolysis of the pigment alkali salt is carried out. Said method is characterized in that an effective quantity of a pigment dispersant of formula (II) is added during the protolysis of the pigment alkali salt. In formula (II), Q is a radical of an organic pigment from the group of perinone, quinacridone, quinacridonquinone, anthanthrone, indanthrone, dioxazine, diketopyrrolopyrrol, indigo, thioindigo, thiazineindigo, isoindoline, isoindolinone, pyranthrone, isoviolanthrone, flavanthrone or anthrapyrimidine pigments.

  该发明涉及一种直接生产精细颗粒1,4-二酮吡咯[3,4-c]吡咯的方法，其中R1a、R1b、R2a和R2b分别表示氢、卤素、C1-C4烷基、C1-C4烷氧基、氰基或苯基，所述化合物的最大频率分布在20至120纳米之间。根据该方法，腈与琥珀酸酯或内酰胺或烯胺在碱性介质中反应形成颜料盐，然后进行颜料碱盐的质子解离。该方法的特点在于在颜料碱盐的质子解离过程中添加有效量的式（II）的颜料分散剂。在式（II）中，Q是来自苯并吡喃、喹啉喹啉醌、蒽醌、吲哚醌、二氧化锌、二酮吡咯吡咯、靛蓝、硫靛蓝、噻吩靛蓝、异吲哚、异吲哚酮、吡喃蒽、异苯并吡啶颜料组中的有机颜料的基团。
• Process for producing dichlorodiketopyrrolopyrrole pigment of the alpha modificaton, dichlorodiketopyrrolopyrrole pigment of the alpha modification produced by the process, and coloring composition using the same
  申请人：Minashima Hidenori

  公开号：US20080022902A1

  公开（公告）日：2008-01-31

  A process for producing dichlorodiketopyrrolopyrrole pigment of the α modification, which comprises wet milling crude dichlorodiketopyrrolopyrrole pigment wherein an α modification and a β modification coexist in the presence of a milling agent and a wetting agent, dichlorodiketopyrrolopyrrole pigment of the α modification obtained the process and a color composition which contains the pigment and a pigment carrier.
• COMPOSITION, METHOD OF MANUFACTURING COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, AND CAMERA MODULE
  申请人：FUJIFILM Corporation

  公开号：US20170174869A1

  公开（公告）日：2017-06-22

  Provided are a composition of which dispersibility of particles including a pyrrolopyrrole coloring agent is satisfactory, a method of manufacturing a composition, a curable composition, a cured film using a curable composition, a near-infrared cut filter, a solid-state imaging device, an infrared sensor, and a camera module. The composition includes particles including a coloring agent represented by Formula (1), in which an average secondary particle diameter of the particles is 500 nm or less. R 1a and R 1b each independently represent an alkyl group, an aryl group, or a heteroaryl group, R 2 and R 3 each independently represent a hydrogen atom or a substituent, R 2 and R 3 may be bonded to each other to form a ring, R 4 's each independently represent a hydrogen atom, an alkyl group, an aryl group, a heteroaryl group, —BR 4A R 4B , or a metal atom, R 4 's may form a covalent bond or a coordinate bond with at least one selected form R 1a , R 1b , or R 3 , and R 4A and R 4B each independently represent a hydrogen atom or a substituent.
• US7431762B2
  申请人：——

  公开号：US7431762B2

  公开（公告）日：2008-10-07