摘要:
A series of novel arylantimony(V) triphenylgermanylpropionates with the formula ((Ph3GeCHRCHRCO2)-C-1-C-2)(n)SbAr(5-n) (R-1 = H, Ph; R-2 =H, CH3; n = 1, 2) were synthesized and characterized by elemental analysis, IR, H-1-NMR, C-13-NMR and mass spectroscopy. The crystal structures of Ph3GeCH(Ph)CH2CO2SbPh4 and [Ph3GeCH2CH(CH3)CO2](2)Sb(4-ClC6H4)(3) were determined by X-ray diffraction. The in vitro antitumor activities of some selected compounds against five cancer cells are reported. (C) 2001 Elsevier Science B.V. All rights reserved.