| 1345491-87-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• CAS: 1345491-87-3
• 化学式: C₂F₆NO₄S₂*C₁₉H₁₅
• 分子量: 523.477
• InChiKey: PWGIOEKWUWQOLY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.77
• 重原子数：
  34.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  82.38
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  、 双三氟甲烷磺酰亚胺 以 二氯甲烷 为溶剂， 反应 0.08h， 生成
  参考文献：
  名称：

  Glycosylation of alcohols using glycosyl boranophosphates as glycosyl donors

  摘要：

  A novel glycosylation that uses glycosyl boranophosphate triesters as glycosyl donors and trityl cation (Tr+) as an activator was developed. Two types of reactions were studied: (1) the boranophosphate triester was activated with TrNTf2 to react with an alcohol and (2) O-trityl ethers worked as both glycosyl acceptors and Tr+ sources. The latter gave better results and the desired O-glycosylation products were rapidly generated and isolated in moderate to good yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.04.032
• 作为试剂：
  描述：

  dimethyl 2,3,4,6-tetra-O-benzyl-D-glucopyranosyl boranophosphate 、 胆固醇 在 triphenylmethylium bis(trifluoromethanesulfonyl)imide 作用下， 以 1,4-二氧六环 、 二氯甲烷 为溶剂， 反应 1.0h， 生成 3-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)cholesterol 、 O-[2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl]cholesterol
  参考文献：
  名称：

  Glycosylation of alcohols using glycosyl boranophosphates as glycosyl donors

  摘要：

  A novel glycosylation that uses glycosyl boranophosphate triesters as glycosyl donors and trityl cation (Tr+) as an activator was developed. Two types of reactions were studied: (1) the boranophosphate triester was activated with TrNTf2 to react with an alcohol and (2) O-trityl ethers worked as both glycosyl acceptors and Tr+ sources. The latter gave better results and the desired O-glycosylation products were rapidly generated and isolated in moderate to good yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.04.032