[5-chloro-2-(3-dimethylaminomethylphenyl)-1H-indole-7-yl]-(tetrahydropyran-4-yl)-amine | 1120334-56-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: [5-chloro-2-(3-dimethylaminomethylphenyl)-1H-indole-7-yl]-(tetrahydropyran-4-yl)-amine
• 英文别名: [5-chloro-2-(3-dimethylaminomethylphenyl)-1H-indol-7-yl]-(tetrahydropyran-4-yl)amine；5-chloro-2-[3-[(dimethylamino)methyl]phenyl]-N-(oxan-4-yl)-1H-indol-7-amine
• CAS: 1120334-56-6
• 化学式: C₂₂H₂₆ClN₃O
• 分子量: 383.921
• InChiKey: VXFRJPJDCSMTHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  40.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS
  申请人：LG Chem, Ltd.

  公开号：EP2178870B1

  公开（公告）日：2018-09-19
• PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS
  申请人：CATHOLIC UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

  公开号：US20150038500A1

  公开（公告）日：2015-02-05

  The invention relates to a pharmaceutical composition for preventing or treating an ophthalmologic disease comprising a compound of formula (1) as defined in the specification, or a pharmaceutically acceptable salt or isomer thereof as an active ingredient. Also, the invention relates to a composition for cleansing or preserving a contact lens comprising the above active ingredient.
• US8436038B2
  申请人：——

  公开号：US8436038B2

  公开（公告）日：2013-05-07