1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-glycinate | 47209-40-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-glycinate
• CAS: 47209-40-5
• 化学式: C₁₄H₂₃NO₇
• 分子量: 317.339
• InChiKey: BKCOMRMJUMPNAQ-DVYMNCLGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.12
• 重原子数：
  22.0
• 可旋转键数：
  3.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  98.47
• 氢给体数：
  1.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-glycinate 、 二苯酮缩亚胺盐酸盐 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 [(3aR,5R,6S,6aR)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 2-(benzhydrylideneamino)acetate
  参考文献：
  名称：

  Synthesis of 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl and 1,2:3,4-di-O-isopropylidene-D-galactopyranos-6-yl-(N-diphenylmethylene) glycinates

  摘要：

  1,2:3,4-di-O-isopropylidene-D-galactopyranos-6-yl-(N-diphenylemthylene)-glycinate 3, was prepared via a trans-esterification process from ethyl (N-diphenylmethylene)-glycinate and 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-(N-diphenylmethylene) glycinate 9, via a trans-imination reaction from 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl glycinate 6 and diphenyl-ketiminium chloride. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00290-x
• 作为产物：
  描述：

  1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-(N-benzyloxycarbonyl)-glycinate 在 palladium on activated charcoal 氢气 作用下， 以 乙酸乙酯 为溶剂， 反应 2.0h， 生成 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-glycinate
  参考文献：
  名称：

  Synthesis of 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl and 1,2:3,4-di-O-isopropylidene-D-galactopyranos-6-yl-(N-diphenylmethylene) glycinates

  摘要：

  1,2:3,4-di-O-isopropylidene-D-galactopyranos-6-yl-(N-diphenylemthylene)-glycinate 3, was prepared via a trans-esterification process from ethyl (N-diphenylmethylene)-glycinate and 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl-(N-diphenylmethylene) glycinate 9, via a trans-imination reaction from 1,2:5,6-di-O-isopropylidene-D-glucofuranos-3-yl glycinate 6 and diphenyl-ketiminium chloride. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00290-x