10-aminodecanyl benzoate | 1143463-95-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 10-aminodecanyl benzoate
• 英文别名: 10-aminodecyl benzoate
• CAS: 1143463-95-9
• 化学式: C₁₇H₂₇NO₂
• 分子量: 277.407
• InChiKey: XRHARTJDNCFHGX-UHFFFAOYSA-N

物化性质

• 沸点：
  385.0±15.0 °C(predicted)
• 密度：
  0.992±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯甲酸甲酯 、 10-氨基-1-癸醇 在 lanthanum(III) isopropoxide 、 二乙二醇单甲醚 作用下， 以 正己烷 为溶剂， 以90%的产率得到10-aminodecanyl benzoate
  参考文献：
  名称：

  Ligand-Assisted Rate Acceleration in Lanthanum(III) Isopropoxide Catalyzed Transesterification of Carboxylic Esters

  摘要：

  The transesterification of an equimolar mixture of carboxylic esters and primary (1 degrees), secondary (2 degrees), and tertiary (3 degrees) alcohols in hydrocarbon solvents was promoted with high efficiency by a lanthanum(III) complex, which was prepared in situ from lanthanum(III) isopropoxide (1 mol %) and 2-(2-methoxyethoxy)ethanol(2 mol %). The present La(III) catalyst was highly effective for the chemoselective transesterification in the presence of competitive 1 degrees- and 2 degrees-amines. Remarkably, esters were obtained in good to excellent yields as colorless materials without an inconvenient workup procedure.

  DOI：

  10.1021/ol102753n

文献信息

• ACYLATION REACTION OF HYDROXYL GROUP
  申请人：Mashima Kazushi

  公开号：US20100249422A1

  公开（公告）日：2010-09-30

  Disclosed is a selective ester production process of an alcoholic hydroxyl group, which proceeds under chemically mild conditions, while having adequate environmental suitability, operability and economical efficiency. Specifically disclosed is a process for producing an ester compound, which is characterized in that an alcohol and a carboxylic acid ester compound are reacted in the presence of a compound containing zinc element, thereby selectively acylating a hydroxyl group of the alcohol.

  公开了一种选择性酯化醇羟基的生产过程，该过程在化学上温和的条件下进行，同时具有足够的环境适应性、操作性和经济效益。具体公开了一种生产酯化合物的方法，其特征在于，在含锌元素的化合物存在下，将醇和羧酸酯化合物反应，从而选择性地酰化醇的羟基。
• Acylation reaction of hydroxyl group
  申请人：Mashima Kazushi

  公开号：US08431709B2

  公开（公告）日：2013-04-30

  Disclosed is a selective ester production process of an alcoholic hydroxyl group, which proceeds under chemically mild conditions, while having adequate environmental suitability, operability and economical efficiency. Specifically disclosed is a process for producing an ester compound, which is characterized in that an alcohol and a carboxylic acid ester compound are reacted in the presence of a compound containing zinc element, thereby selectively acylating a hydroxyl group of the alcohol.

  本发明揭示了一种选择性醇羟基酯的生产过程，该过程在化学温和条件下进行，同时具有充分的环境适应性、可操作性和经济效益。具体揭示了一种制备酯类化合物的过程，其特征在于，在含锌元素的化合物存在下，醇和羧酸酯类化合物反应，从而选择性地酰化醇的羟基。
• EP2196451
  申请人：——

  公开号：——

  公开（公告）日：——
• US8431709B2
  申请人：——

  公开号：US8431709B2

  公开（公告）日：2013-04-30