3,10,19,26-Tetraoxa-tricyclo[26.4.0.0^12,17]dotriaconta-1(28),12(17),13,15,29,31-hexaene-2,11,18,27-tetraone | 55379-43-6

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: 3,10,19,26-Tetraoxa-tricyclo[26.4.0.0^12,17]dotriaconta-1(28),12(17),13,15,29,31-hexaene-2,11,18,27-tetraone
• 英文别名: Cyclic 1,6-HD-PA-1,6-HD-PA；3,10,19,26-tetraoxatricyclo[26.4.0.012,17]dotriaconta-1(32),12,14,16,28,30-hexaene-2,11,18,27-tetrone
• CAS: 55379-43-6
• 化学式: C₂₈H₃₂O₈
• 分子量: 496.557
• InChiKey: QYBCKUJHXFQNEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  36
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  二苯硫醚 在 silver tetrafluoroborate 、 caesium carbonate 作用下， 以 丙酮 为溶剂， 反应 12.0h， 生成 3,10,19,26-Tetraoxa-tricyclo[26.4.0.0^12,17]dotriaconta-1(28),12(17),13,15,29,31-hexaene-2,11,18,27-tetraone
  参考文献：
  名称：

  Synthesis of macrocyclic dilactones by cyclization of sulfonium salts

  摘要：

  An efficient method for the formation of macrocyclic dilactones via cyclization of (omega-carboxyalkyl)diphenylsulfonium salts 3 containing an ester linkage under mild conditions is described. These sulfonium salts 3 were cyclized in the presence of cesium carbonate under high-dilution conditions to give 11- to 16-membered dilactones 4 in good yields. The cyclization of sulfonium salt 22 was successfully carried out for the synthesis of 11-membered dilactonic pyrrolizidine alkaloid, 13,13-dimethyl-1,2-didehydrocrotalanine 23.

  DOI：

  10.1021/jo00040a013

文献信息

• A Fluorescent Compound from the Exuviae of the Scorpion, <i>Liocheles australasiae</i>
  作者：Yusuke Yoshimoto、Masato Tanaka、Masahiro Miyashita、Mohammed Abdel-Wahab、Alhussin M. A. Megaly、Yoshiaki Nakagawa、Hisashi Miyagawa

  DOI：10.1021/acs.jnatprod.9b00972

  日期：2020.2.28

  types of fluorescent compounds have been identified in scorpions, but it has been assumed that other unknown compounds may be responsible for the fluorescence. In this study, we isolated a fluorescent compound from the exuviae of the scorpion Liocheles australasiae identified as a macrocyclic diphthalate ester with a molecular mass of 496.2 Da. The same compound was also detected in extracts from four

  大多数蝎子在紫外线下发出荧光。迄今为止，在蝎子中已经鉴定出两种类型的荧光化合物，但是已经假定其他未知化合物可能是造成荧光的原因。在这项研究中，我们从蝎子Liocheles australasiae的足突中分离出一种荧光化合物，该化合物被鉴定为分子量为496.2 Da的大环二邻苯二甲酸酯。在其他四种蝎子的提取物中也检测到相同的化合物。这表明该化合物为多种蝎子所共有，尽管其对角质层荧光的贡献可能相对较小。
• IMMUNOSTIMULATOR AND FOOD OR BEVERAGE FOR IMMUNOSTIMULATION
  申请人：AMINO UP CO., LTD.

  公开号：US20220151985A1

  公开（公告）日：2022-05-19

  An immunostimulator that comprises a compound represented by general formula I (wherein n stands for an integer of 4-12) or a pharmacologically acceptable salt thereof as an active ingredient.