resorufin levulinate | 1258210-06-8

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: resorufin levulinate
• 英文别名: (7-oxophenoxazin-3-yl) 4-oxopentanoate
• CAS: 1258210-06-8
• 化学式: C₁₇H₁₃NO₅
• 分子量: 311.294
• InChiKey: UUMNIYNJRFUDAV-UHFFFAOYSA-N

物化性质

• 沸点：
  498.8±45.0 °C(Predicted)
• 密度：
  1.35±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  82
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  resorufin levulinate 在 sulfites 作用下， 生成 Sodium;2-methyl-5-oxooxolane-2-sulfonate 、 7-hydroxy-3H-phenoxazin-3-one sodium salt
  参考文献：
  名称：

  Chromogenic and Fluorogenic Signaling of Sulfite by Selective Deprotection of Resorufin Levulinate

  摘要：

  A new sulfite-selective probe system based on resorufin was investigated. Levulinate of resorufin exhibited a prominent chromogenic and turn-on type fluorogenic signaling toward sulfite ions in aqueous media based on the selective deprotection of the levulinate group. The sulfite-selective signaling was possible in the presence of commonly encountered anions.

  DOI：

  10.1021/ol102298b
• 作为产物：
  描述：

  5-氧代己酸 在 草酰氯 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 16.0h， 生成 resorufin levulinate
  参考文献：
  名称：

  Chromogenic and Fluorogenic Signaling of Sulfite by Selective Deprotection of Resorufin Levulinate

  摘要：

  A new sulfite-selective probe system based on resorufin was investigated. Levulinate of resorufin exhibited a prominent chromogenic and turn-on type fluorogenic signaling toward sulfite ions in aqueous media based on the selective deprotection of the levulinate group. The sulfite-selective signaling was possible in the presence of commonly encountered anions.

  DOI：

  10.1021/ol102298b

文献信息

• Sensor Comprising Resrufin Levulinate Having Sulfite Ion Selectivity and Method for Monitoring Sulfite Ion Using the Same
  申请人：CHANG Suk-Kyu

  公开号：US20120135532A1

  公开（公告）日：2012-05-31

  The present invention relates to a sensor comprising a resorufin compound having sulfite ion selectivity and a method for detecting sulfite ions using the same. More specifically, the resorufin compound may have outstandingly increased fluorescence intensity by a deprotection reaction that a levulinyl group is cleaved with a sulfite ion to be used as a selective fluorescence sensor of turn-on type, and also represent a chromogenic change to detect sulfite ions by naked eye.

  本发明涉及一种传感器，其包括具有亚硫酸盐离子选择性的荧光素化合物，并且涉及使用该传感器检测亚硫酸盐离子的方法。更具体地说，该荧光素化合物可以通过去保护反应（即通过亚硫酸盐离子裂解丙酰丙酸酯基团）显著增加荧光强度，用作一种选择性的“开启型”荧光传感器，并且通过肉眼观察表示出色变以检测亚硫酸盐离子。